Formic Acid, LC-MS Grade, ≥98%

Name: Formic Acid, LC-MS Grade, ≥98%
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Cat.No: ATR-SDS-0008 Datasheet

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Product Name	Formic Acid, LC-MS Grade, ≥98%
Catalog No.	ATR-SDS-0008
Description	Ultra-pure formic acid with extremely low metal content and background signal, optimized as a mobile phase additive in liquid chromatography-mass spectrometry for peptide and small molecule analysis.
Intended Use	Mobile phase modifier for LC-MS analysis of peptides, proteins, and metabolites; dissolution agent for proteomics sample preparation; pH adjustment in electrospray ionization-compatible solvents.
Principle / Technology	Formic acid (0.1% v/v) provides protons for positive-mode electrospray ionization, enhancing peptide ionization efficiency while maintaining volatile properties that prevent ion source contamination.
Detection Method	LC-MS purity grade: metal content by ICP-MS, UV absorbance, total ion chromatogram background
Sample Type	Tryptic peptides, intact proteins, metabolites, pharmaceutical compounds for LC-MS analysis
Performance Range / Specifications	Purity ≥98%; Na <0.1 ppm; K <0.1 ppm; Fe <0.05 ppm; 50 ppb metal specification
Sensitivity / LOD	N/A
Specificity	N/A
Reaction Conditions / Protocol	Prepare 0.1% v/v in water or water-acetonitrile mixture for LC-MS mobile phase; freshly prepare working solutions weekly.
Components / Formulation	Formic acid, double-distilled, packed in acid-leached glass or PFA bottle
Storage Conditions	15–30°C, corrosive, store in well-ventilated area
Shelf Life	24 months
Package Specifications	50 mL, 100 mL, 500 mL
Product Form	Liquid
Quality Control	ICP-MS metal analysis, UV/Vis absorbance, LC-MS gradient blank evaluation, non-volatile residue
Key Features	LC-MS tested; ultra-low metal content; minimal ion suppression; packaged to prevent contamination; validated for proteomics and metabolomics

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For research use only, not for clinical use.