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| Product Name | Wide-pH Hybrid Silica Reversed-Phase Packing with C18/C8 Options |
| Catalog No. | IGM-HMM-0248 |
| Description | The Alta DiagnoTech hybrid silica packing combines the mechanical strength of high-purity silica with improved resistance to acidic and alkaline mobile phases. Reduced residual silanol effects help limit nonspecific adsorption and support sharper reversed-phase separation of basic compounds. |
| Intended Use | Reversed-phase separation and purification of acidic and basic compounds using C18 or C8 bonded phases. |
| Principle / Technology | Reversed-phase chromatography on hybrid silica with C18 or C8 bonded phases. |
| Performance Range / Specifications | Operating pH range 1-11; the aqueous portion of the mobile phase should remain below 95%; C18 and C8 bonded-phase options available. |
| Package Specifications | 100 g, 500 g, 1 kg, 5 kg, 10 kg and 20 kg |
| Product Form | Hybrid silica reversed-phase chromatography packing |
| Key Features | pH 1-11 operating range C18 and C8 bonded-phase options Reduced residual silanol effects Improved acid/base durability |
| Application Notes / Precautions | Keep the aqueous portion of the mobile phase below 95%. |
| Product Type | Hybrid silica reversed-phase packing |
| Function / Efficacy | Reversed-phase separation with improved suitability for basic compounds. |
| Customization | Preparative columns are available with 10, 21.2, 30 or 50 mm internal diameters and 100, 150 or 250 mm lengths; other formats or bonded phases may be customized. |
| Chromatography Mode | Reversed-phase chromatography |
| Matrix | Hybrid silica |
| Ligand / Bonded Phase | C18 or C8 |
| pH Stability | Operating pH range 1-11 |
| Chemical Stability | The hybrid structure is described as improving durability under acidic and alkaline conditions. |
For research use only, not for clinical use.
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