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| Product Name | Whole blood, serum, plasma single drug assay kit, 80 ng/mL |
| Catalog No. | CD-00134 |
| Description | Whole blood, serum, plasma single drug assay kit is a test for analyzing whole blood, serum or plasma with high sensitivity and specificity and a detection limit of 80 ng/mL. |
| Sample Type | Urine |
| Application | This product can be used to analyze whole blood, serum or plasma. |
| Operating Temperature | Store at 4-30°C. |
| Transportation Condition | Transportation at room temperature. |
| Cut Off | 80 ng/mL |
In modern biomedical research and preclinical drug development, accurate and reliable detection of drug concentrations in biological matrices is critical for understanding drug pharmacokinetics (PK), pharmacodynamics (PD), and ensuring the safety and efficacy of potential therapeutic agents. Among various biological samples, whole blood, serum, and plasma are the most commonly used matrices—they serve as the primary carriers of drugs and their metabolites in the body, and the drug concentrations in these samples directly reflect the drug’s distribution, absorption, metabolism, and excretion processes.
However, researchers often face significant challenges when analyzing drug concentrations in these complex biological matrices:
Matrix interference: Whole blood, serum, and plasma contain a large number of proteins, lipids, and other biomolecules that can non-specifically bind to detection reagents, leading to false positive/negative results or reduced detection accuracy.
Low drug concentration: In many preclinical studies (e.g., early pharmacokinetic evaluations or low-dose drug testing), the target drug concentration in biological samples is extremely low, requiring assays with high sensitivity to capture these trace levels.
Sample variability: Differences in sample collection, processing (e.g., centrifugation speed, anticoagulant use), and storage conditions can affect the stability of drug molecules and further impact detection results, demanding assays that are robust to such variations.
Need for versatility: Researchers often work with multiple sample types (whole blood, serum, plasma) depending on the study design, making it essential to have assay kits that can accommodate different matrices without compromising performance.
Against this backdrop, the Whole Blood, Serum, Plasma Single Drug Assay Kit (Cat.No: CD-00134) is developed to address these critical pain points. With a detection limit of 80 ng/mL, this kit is specifically optimized for the quantitative analysis of target drugs in whole blood, serum, and plasma samples—providing a reliable, efficient solution for preclinical drug research, pharmacokinetic studies, and drug concentration monitoring in experimental models. It aligns with the core needs of research laboratories, academic institutions, and biotech companies focused on drug development, ensuring that researchers can obtain accurate, reproducible data to support their studies.
Broad Sample Compatibility: Designed to analyze three common biological matrices (whole blood, serum, and plasma), eliminating the need for multiple specialized kits and simplifying experimental workflows for researchers working with diverse sample types.
High Sensitivity and Specificity: Features a detection limit of 80 ng/mL, enabling the accurate capture of low-concentration target drugs in complex biological samples. Its specific binding design minimizes non-specific interference from proteins, lipids, and other biomolecules in matrices, ensuring reliable and accurate quantitative results.
Convenient Storage and Transportation: Requires storage only at 4-30°C (a typical ambient temperature range for laboratory refrigerators or room storage) and supports room-temperature transportation. This reduces the need for cold-chain logistics, lowers storage and transportation costs, and ensures product stability even during long-distance shipping.
Clear Cut-Off Value: Predefined cut-off value of 80 ng/mL provides a clear reference standard for quantitative analysis, helping researchers quickly judge whether the detected drug concentration meets experimental thresholds and simplifying result interpretation.
Simplifies Experimental Workflows: By supporting three key sample types, it reduces the time and effort spent on switching between different kits or adapting protocols for different matrices, allowing researchers to focus more on data collection and analysis.
Cost-Effective Solution: Eliminates the need to purchase separate kits for whole blood, serum, and plasma testing, reducing overall procurement costs. Additionally, its room-temperature transportation and ambient storage requirements lower logistics and storage expenses compared to kits that require frozen storage.
Reliable Performance for Low-Concentration Samples: The 80 ng/mL detection limit addresses the common challenge of detecting low drug concentrations in preclinical studies, ensuring that even trace levels of target drugs are not missed—critical for early pharmacokinetic evaluations and low-dose drug research.
User-Friendly for Diverse Settings: Its simple storage requirements and straightforward operation make it suitable for both well-equipped central laboratories and smaller research facilities with limited specialized storage or equipment, expanding its applicability across different research environments.
Supports Reproducible Research: Consistent batch-to-batch quality and specific design minimize result variability caused by matrix interference or storage/transportation issues, ensuring that data from different experiments or batches is comparable—essential for validating research findings.
For research use only, not for clinical use.
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