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| Product Name | Uracil DNA Glycosylase (UDG/UNG) (1 U/uL) |
| Catalog No. | IVDRM-0575 |
| Description | A contamination-control uracil-DNA glycosylase that catalyses hydrolysis of the N-glycosidic bond between uracil bases and the sugar-phosphate backbone of uracil-containing DNA, releasing free uracil. The enzyme acts on single and double stranded DNA carrying dU and has no activity on RNA, which suits PCR carryover contamination control and removal of uracil bases in DNA deamination repair research. |
| Intended Use | PCR carryover contamination control and removal of uracil bases from single or double stranded DNA |
| Principle / Technology | Hydrolysis of the N-glycosidic bond of uracil in DNA, releasing free uracil |
| Sample Type | dU-containing single and double stranded DNA |
| Specificity | Acts on dU-containing single and double stranded DNA; no activity on RNA |
| Reaction Conditions / Protocol | Pre-treat the reaction with the enzyme to degrade dU carryover before amplification |
| Storage Conditions | -25 to -15°C |
| Shelf Life | 2 years |
| Package Specifications | 100 U; 500 U; 10,000 U |
| Key Features | RNA-inert specificity for DNA uracil excision |
| Concentration | 1 U/uL |
| Readouts / Downstream Assays | Carryover contamination control verified by qPCR |
For in vitro diagnostic use.
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