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| Product Name | Penicillin-Streptomycin-Neomycin Solution, 100×, Sterile |
| Catalog No. | RERE-0342 |
| Description | This triple antibiotic supplement combines the joint antibacterial strength of penicillin, streptomycin and neomycin against both gram-positive and gram-negative bacteria, guarding cell cultures against bacterial contamination. Penicillin, first purified from the fungus Penicillium, disrupts bacterial cell wall synthesis directly and indirectly by triggering release of enzymes that further remodel the wall. Streptomycin, derived from Streptomyces griseus, and neomycin, from Streptomyces fradiae, both bind the 30S ribosomal subunit and halt protein synthesis in sensitive organisms. Each millilitre of the solution carries 5 mg of penicillin, 5 mg of streptomycin and 10 mg of neomycin in 0.85% saline. |
| Intended Use | Protection of cell cultures against bacterial contamination, with extended gram-negative coverage from neomycin. |
| Principle / Technology | Penicillin blocks cell wall assembly while streptomycin and neomycin bind the 30S ribosomal subunit to suppress protein synthesis. |
| Specificity | Penicillin 5 mg/mL; streptomycin 5 mg/mL; neomycin 10 mg/mL; prepared in 0.85% saline; 100× concentrate. |
| Reaction Conditions / Protocol | Dilute into the culture medium at the recommended working strength. |
| Storage Conditions | -20°C; 12 months. |
| Package Specifications | 500 mL |
| Key Features | Three-antibiotic formulation; broad gram-positive and gram-negative coverage; saline-based 100× concentrate. |
For research use only, not for clinical use.
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