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| Product Name | Methylation-Preserving DNA Fragmentation Enzyme Mix |
| Catalog No. | IVDRM-0323 |
| Description | An enzyme cocktail designed and optimised for sample fragmentation upstream of methylation library preparation. Unlike conventional fragmentation enzymes it preserves methylation marks, and compared with ultrasonication it damages templates less, loses less sample and removes the need for sonication hardware. |
| Intended Use | Fragmentation of DNA ahead of methylation library construction and epigenetic sequencing workflows. |
| Principle / Technology | Controlled enzymatic cleavage generates sequencing-sized fragments while leaving methylated bases chemically untouched. |
| Sample Type | Genomic DNA, FFPE DNA from animal, plant and microbial sources |
| Performance Range / Specifications | Input 5 ng to 250 ng; low sample loss |
| Specificity | Preserves methylation marks through fragmentation |
| Storage Conditions | Store at -25 to -15°C |
| Shelf Life | 1 year |
| Package Specifications | 8 T / 24 T / 96 T |
| Product Form | Enzyme mix |
| Key Features | Methylation-preserving chemistry; simpler than sonication; gentle on templates including FFPE DNA |
For in vitro diagnostic use.
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