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| Product Name | Human Platelet Lysate, Xeno-Free Serum Replacement for Cell Culture |
| Catalog No. | RERE-0021 |
| Description | Human platelet lysate is a premium serum replacement rich in natural growth factors and cytokines. This preparation is made from platelets of healthy donors at EU-certified blood banks, so it supports primary cells and cell lines safely and efficiently, with especially strong promotion of stem cell, immune cell and other human-derived cell proliferation while preserving differentiation potential. A dedicated process removes fibrinogen, the product carries no xeno-added substances and no heparin, and it replaces fetal bovine serum and human AB serum directly. Batch sizes are large with high lot-to-lot consistency, which keeps long experiments comparable. |
| Intended Use | Direct replacement for fetal bovine serum and human AB serum in the 2D or 3D culture of mesenchymal stem cells, T cells, induced pluripotent stem cells, tumour cells, fibroblasts and other primary cells or cell lines. |
| Principle / Technology | Platelet granules carry a natural payload of growth factors and cytokines; lysing the platelets releases this supplement into a defined, xeno-free medium additive, with fibrinogen removed to keep cultures clean. |
| Detection Method | Performance is judged by culture outcomes - proliferation, clonogenicity, differentiation potential and immunosuppressive activity measured by the laboratory. |
| Sample Type | Cultured cells supplemented with hPL in place of serum. |
| Performance Range / Specifications | Source: platelets from EU-certified blood banks; endotoxin-free; fibrinogen removed; heparin-free; xeno-free; high lot-to-lot consistency; supports MSC, T cells, iPSC, tumour cells and fibroblasts; maintains clonogenic capacity, trilineage potential and T-cell immunosuppressive activity; 50 mL bottle. |
| Specificity | Human-derived supplement intended as a drop-in replacement for animal sera; no heparin added. |
| Reaction Conditions / Protocol | Thaw, mix gently, and add directly into the culture formulation in place of the serum it replaces; keep handling aseptic and avoid repeated freeze-thaw cycles. |
| Components / Formulation | One 50 mL bottle of human platelet lysate. |
| Storage Conditions | Store at -25 to -15 °C. |
| Shelf Life | 24 months under the recommended storage conditions. |
| Package Specifications | 50 mL per bottle |
| Product Form | Frozen liquid supplement. |
| Quality Control | Lot release covers endotoxin absence, fibrinogen depletion, heparin-free status and batch-to-batch consistency. |
| Key Features | - Direct replacement for FBS and human AB serum - From EU-certified blood bank platelets - Endotoxin-free, fibrinogen-depleted and heparin-free - Large batches with high lot-to-lot consistency - Supports MSCs, T cells, iPSCs, tumour cells and fibroblasts |
| Concentration | Supplied as a liquid; the working supplement level is set by the user's culture formulation. |
| Activity / Unit Definition | Performance is defined by the documented promotion of proliferation while maintaining clonogenicity, trilineage potential and T-cell immunosuppressive activity. |
| Source / Origin | Platelets of healthy donors from EU-certified blood banks. |
| Shipping Conditions | Shipped frozen on dry ice. |
| Expiration Date / Stability | Stable through the stated shelf life when kept protected from light at the recommended storage temperature. |
| Regulatory / Compliance | For research use only. |
| Compatibility | Suitable for 2D and 3D culture of MSCs, T cells, iPSCs, tumour cells, fibroblasts and a broad range of primary cells and cell lines. |
| Recommended Buffer System | No separate buffer is supplied; the lysate is added directly into the culture formulation. |
| Application Notes / Precautions | Thaw gently and aliquot to avoid repeated freeze-thaw cycles, keep handling aseptic, and validate the working supplement level for each cell type before scaling up. |
| Batch-to-Batch Consistency | Large single-batch output with high lot-to-lot consistency keeps long experiments comparable. |
| Model Type | Xeno-free serum replacement (platelet lysate) |
| Starting Material / Tissue Site | Platelets of healthy donors from EU-certified blood banks, processed to remove fibrinogen |
| Delivery Standard | 50 mL bottle |
| Readouts / Downstream Assays | Proliferation, clonogenicity, differentiation and immunosuppression assays run by the user laboratory. |
For research use only, not for clinical use.
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