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| Product Name | HIV-1 PR/RT Drug-Resistance Genotyping PCR-Sequencing Kit 2×10^3 copies/mL LOD |
| Catalog No. | CS-DB-0032 |
| Description | The Alta DiagnoTech HIV-1 drug-resistance genotyping kit automates PCR amplification and sequencing of the viral PR and RT regions. It covers resistance-associated mutations linked to protease inhibitors, nucleoside reverse-transcriptase inhibitors and non-nucleoside reverse-transcriptase inhibitors. |
| Intended Use | Genotypic assessment of HIV-1 resistance-associated variants relevant to three major antiretroviral drug classes. |
| Principle / Technology | Automated PCR amplification and sequencing of HIV-1 PR and RT genomic regions. |
| Detection Method | PCR sequencing |
| Performance Range / Specifications | Forty-four PR/RT positions and more than 100 mutation types; stated detection limit is 2×10^3 copies/mL. |
| Sensitivity / LOD | 2×10^3 copies/mL |
| Specificity | No cross-reactivity was reported with HBV, HCV, HTLV or EBV. |
| Key Features | PR and RT region coverage Forty-four resistance-associated positions More than 100 mutation types Automated amplification and sequencing |
| Product Type | Viral drug-resistance genotyping kit |
| Analytes / Targets | HIV-1 protease (PR) and reverse-transcriptase (RT) regions |
| Genotypes / Variants Detected | More than 100 mutation types across 44 positions associated with protease inhibitors, NRTIs and NNRTIs. |
| Interference | Results are not affected by interfering substances; individual interferents are not listed. |
For research use only, not for clinical use.
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