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| Product Name | HBV RT-Region Drug-Resistance PCR-Sanger Kit for More Than 20 Mutations |
| Catalog No. | CS-DB-0035 |
| Description | The Alta DiagnoTech hepatitis B virus drug-resistance mutation kit uses PCR followed by Sanger sequencing to analyze the HBV reverse-transcriptase region from positions 143-280. It covers more than 20 resistance-associated mutations linked to six nucleoside/nucleotide analogue drugs and can report resistance findings together with HBV genotype information. |
| Intended Use | Detection of hepatitis B virus mutations associated with antiviral drug resistance and simultaneous HBV genotyping. |
| Principle / Technology | PCR amplification followed by Sanger sequencing with software-assisted report generation and UDG carryover prevention. |
| Detection Method | PCR-Sanger sequencing |
| Sample Type | Serum or plasma specimens |
| Performance Range / Specifications | HBV RT-region positions 143-280; more than 20 resistance-associated mutations linked to six nucleoside/nucleotide analogue drugs; stated applicable viral-load range is 1×10^3-5×10^8 IU/mL. |
| Sensitivity / LOD | Stated applicable viral-load range: 1×10^3-5×10^8 IU/mL |
| Components / Formulation | UDG contamination-control system. |
| Key Features | HBV RT positions 143-280 More than 20 resistance-associated mutations Simultaneous resistance and genotype analysis Sanger sequencing with software-generated reports |
| Product Type | Hepatitis B drug-resistance mutation detection kit |
| Analytes / Targets | Hepatitis B virus reverse-transcriptase region, positions 143-280 |
| Genotypes / Variants Detected | More than 20 HBV resistance-associated mutations linked to six nucleoside/nucleotide analogue drugs; individual mutations are not specified |
For research use only, not for clinical use.
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