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| Product Name | Mycobacterium tuberculosis Isoniazid-Resistance PCR-Sequencing Kit for katG/inhN/ahpC |
| Catalog No. | CS-DB-0033 |
| Description | The Alta DiagnoTech isoniazid-resistance mutation kit uses PCR sequencing to analyze Mycobacterium tuberculosis resistance-associated loci in sputum specimens. Coverage includes katG, inhN and ahpC sites, with common changes such as katG 315 AGC→ACC and the promoter -15 C→T substitution. |
| Intended Use | Detection of Mycobacterium tuberculosis gene mutations associated with isoniazid resistance. |
| Principle / Technology | PCR amplification followed by sequencing, with UNG/UDG and dUTP carryover-contamination control. |
| Detection Method | PCR sequencing |
| Sample Type | Sputum specimens |
| Performance Range / Specifications | Coverage includes mutation sites in katG, inhN and ahpC; common changes listed on the page include 315 AGC→ACC and promoter -15 C→T; results can be produced in approximately 24 hours. |
| Components / Formulation | UNG/UDG enzyme and dUTP contamination-control system. |
| Key Features | katG, inhN and ahpC mutation coverage Common 315 AGC→ACC and -15 C→T sites Approximately 24-hour result time UNG/UDG-dUTP carryover prevention |
| Product Type | Tuberculosis drug-resistance mutation detection kit |
| Analytes / Targets | Mycobacterium tuberculosis isoniazid-resistance loci: katG, inhN and ahpC |
| Genotypes / Variants Detected | Mutation sites across katG, inhN and ahpC, including 315 AGC→ACC and promoter -15 C→T |
For research use only, not for clinical use.
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