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| Product Name | HBV YMDD rtM204I/V and rtL180M PCR-Reverse Dot-Blot Kit |
| Catalog No. | CS-DB-0038 |
| Description | The Alta DiagnoTech hepatitis B virus YMDD mutation kit combines PCR with reverse dot-blot hybridization. It detects rtM204I and rtM204V mutations in the HBV C region plus the rtL180M mutation in the B region. |
| Intended Use | Detection of HBV YMDD-region mutations rtM204I, rtM204V and rtL180M. |
| Principle / Technology | PCR amplification followed by reverse dot-blot hybridization. |
| Detection Method | PCR-reverse dot-blot hybridization |
| Performance Range / Specifications | Three listed HBV mutations; stated detection limit is no higher than 5,000 IU/mL; sample processing can use the included extraction solution or magnetic-bead extraction reagents. |
| Sensitivity / LOD | ≤5,000 IU/mL |
| Specificity | No cross-reactivity was reported with HCV, HIV-1 or Treponema pallidum. |
| Components / Formulation | Sample extraction solution, positive control and negative control; magnetic-bead extraction reagents may also be used. |
| Quality Control | Positive and negative controls monitor the complete testing workflow. |
| Key Features | rtM204I, rtM204V and rtL180M detection ≤5,000 IU/mL stated detection limit Two supported extraction approaches Full-process positive and negative controls |
| Product Type | Hepatitis B mutation detection kit |
| Analytes / Targets | HBV YMDD-associated regions |
| Genotypes / Variants Detected | rtM204I, rtM204V and rtL180M |
For research use only, not for clinical use.
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