GMP-Grade Inorganic Pyrophosphatase for Improved RNA Yield (1 U/uL)
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GMP-Grade Inorganic Pyrophosphatase for Improved RNA Yield (1 U/uL)

Cat.No: IVDRM-0352 Datasheet

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Product Name GMP-Grade Inorganic Pyrophosphatase for Improved RNA Yield (1 U/uL)
Catalog No. IVDRM-0352
Description Recombinantly expressed in E. coli, this inorganic pyrophosphatase splits one molecule of pyrophosphate into two phosphate ions, a strongly exergonic step that can be coupled to thermodynamically unfavourable reactions to drive them to completion. Including the enzyme in reverse transcription and in vitro transcription pulls the equilibrium toward product and measurably raises RNA yield, and it supports mRNA programs through IND filing. Produced free of ampicillin and any animal-derived raw materials under GMP requirements with an ISO 13485 system and drug master file filed.
Intended Use Yield improvement in in vitro transcription for mRNA manufacturing; RNA yield enhancement in reverse transcription reactions.
Specificity Free of ampicillin and animal-derived raw materials; optimal temperature 25 °C
Storage Conditions -25 °C to -15 °C
Shelf Life 12 months
Package Specifications 10 U, 100 U, 1000 U and 40 KU packs
Product Form Liquid
Concentration 1 U/uL
Source / Origin Recombinant E. coli
Regulatory / Compliance GMP grade; ISO 13485 quality system; drug master file filed
Recommended Buffer System 50 mM Tris-HCl pH 7.9, 100 mM NaCl, 10 mM DTT, 1 mM EDTA, 0.1% Triton X-100, 50% glycerol
Model Type Inorganic pyrophosphatase, GMP grade

For in vitro diagnostic use.

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