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| Product Name | G418 Solution, 20 mg/mL, Sterile (Geneticin) |
| Catalog No. | RERE-0328 |
| Description | G418, also called geneticin, is an aminoglycoside related to neomycin that is toxic to bacteria, yeasts, higher plants, protozoa and mammalian cells. It is the standard agent for selecting eukaryotic cells that carry aminoglycoside resistance markers. The product is a sterile solution adjusted to pH 7.2-7.9. |
| Intended Use | Selection of stably transfected eukaryotic cells carrying aminoglycoside resistance constructs. |
| Principle / Technology | The aminoglycoside interferes with protein synthesis in sensitive cells, eliminating non-resistant lines while resistant clones survive. |
| Specificity | 20 mg/mL; sterile solution; pH 7.2-7.9; CAS 108321-42-2. |
| Reaction Conditions / Protocol | Add to culture medium at a working concentration of 50-1000 µg/mL according to the sensitivity of the host line. |
| Storage Conditions | -20°C; protected from light; 12 months. |
| Package Specifications | 10 mL |
| Key Features | Broad activity across bacteria, yeast, plants, protozoa and mammalian cells; sterile and ready to dilute; typical working range 50-1000 µg/mL. |
For research use only, not for clinical use.
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