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| Product Name | G418 Solution, 100 mg/mL, Sterile (Geneticin) |
| Catalog No. | RERE-0343 |
| Description | G418, also known as geneticin, is a neomycin-related aminoglycoside toxic to bacteria, yeasts, higher plants, protozoa and mammalian cells, making it a standard agent for selecting eukaryotic cells that carry aminoglycoside resistance markers. This high-concentration sterile stock is adjusted to pH 7.2-7.9 and supports economical dosing across many selection experiments. |
| Intended Use | Selection of stably transfected eukaryotic cells carrying aminoglycoside resistance constructs from a concentrated stock. |
| Principle / Technology | The aminoglycoside disrupts protein synthesis in sensitive cells, so only resistant clones survive selection. |
| Specificity | 100 mg/mL; sterile solution; pH 7.2-7.9; CAS 108321-42-2. |
| Reaction Conditions / Protocol | Dilute aseptically to a working concentration of 50-1000 µg/mL according to host line sensitivity. |
| Storage Conditions | -20°C; protected from light; 12 months. |
| Package Specifications | 10 mL |
| Key Features | Concentrated 100 mg/mL format; broad activity across eukaryotic systems; typical working range 50-1000 µg/mL. |
For research use only, not for clinical use.
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