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| Product Name | Engineered tRNA Adenosine Deaminase (ecTadA) |
| Catalog No. | IVDRM-0315 |
| Description | An engineered mutant of the E. coli tRNA-specific adenosine deaminase, produced recombinantly at purity above 95%. The native enzyme deaminates adenine in single-stranded RNA, mainly within transfer RNA loops, and in double-stranded RNA, with no activity on DNA; this engineered variant deaminates adenine in single-stranded DNA efficiently, which opens up adenine base editing and RNA m6A methylation sequencing applications. |
| Intended Use | Adenine base editing (ABE) workflows and library preparation for RNA m6A methylation sequencing. |
| Detection Method | Adenine in single-stranded DNA (engineered) and in single-stranded or double-stranded RNA (native activity) |
| Performance Range / Specifications | Purity above 95%; efficient deamination of adenine in single-stranded DNA |
| Specificity | Engineered for single-stranded DNA activity; native enzyme acts on RNA with no DNA deamination |
| Storage Conditions | -85 to -65 °C |
| Shelf Life | 1 year |
| Package Specifications | 20 µg, 100 µg |
| Purity | Above 95% |
| Source / Origin | Escherichia coli tRNA-specific adenosine deaminase mutant, recombinantly expressed |
For in vitro diagnostic use.
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