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| Product Name | Chloramphenicol Solution, 34 mg/mL, Sterile |
| Catalog No. | RERE-0332 |
| Description | Chloramphenicol, originally isolated by David Gottlieb from Streptomyces venezuelae, is a broad-spectrum bacteriostatic antibiotic. It blocks the peptidyl transferase of the bacterial 50S ribosomal subunit and thereby halts translation; at high concentrations it can also suppress eukaryotic DNA synthesis. In molecular biology it serves as the selection agent for plasmids carrying chloramphenicol resistance determinants. |
| Intended Use | Screening of chloramphenicol resistance markers in molecular biology workflows. |
| Principle / Technology | Inhibition of peptidyl transferase on the 50S subunit stops bacterial protein biosynthesis. |
| Specificity | 34 mg/mL; sterile solution; CAS 56-75-7. |
| Reaction Conditions / Protocol | Supplement media at working concentrations of 25-170 µg/mL depending on the application. |
| Storage Conditions | -20°C; protected from light; 12 months. |
| Package Specifications | 10 mL |
| Key Features | Broad-spectrum bacteriostatic action; standard selection agent for chloramphenicol-resistant constructs; typical working range 25-170 µg/mL. |
For research use only, not for clinical use.
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