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| Product Name | Acridinium Ester Series Six Chemiluminescent Labels >=98% Purity for Immunoassay |
| Catalog No. | IGM-HMM-0103 |
| Description | This acridinium ester series comprises six distinct chemiluminescent labeling reagents, including acridinium esters (types 0-3), acridinium sulfonamide salts (types 4-5), and acridinium hydrazide (type 6). All compounds share a common acridinium ring as the light-emitting core but differ in reactive groups, hydrophilicity, and stability profiles. Types 0-3 are NHS-active esters suitable for direct coupling to protein amine groups. Types 4-6 incorporate sulfopropyl groups for enhanced water solubility, with type 5 requiring EDCI activation and type 6 featuring a hydrazide group for aldehyde-reactive conjugation. All variants exhibit >=98% purity and demonstrate comparable luminescence performance. Types 1-3 offer enhanced hydrolytic stability compared to type 0, while types 4-6 show superior stability in acidic conditions and can be stored for over one year at -20°C as lyophilized conjugates. |
| Intended Use | For use as chemiluminescent labels in immunoassay development, antibody labeling, nucleic acid conjugation, and diagnostic kit manufacturing. |
| Principle / Technology | Direct chemiluminescence: all acridinium derivatives react with alkaline hydrogen peroxide to generate excited-state N-methylacridone, which emits light at 430 nm upon returning to ground state. NHS esters (types 0-4) couple directly to primary amines; type 5 requires carbodiimide activation; type 6 reacts with aldehyde groups. |
| Detection Method | Chemiluminescence detection at 430 nm with flash-type kinetics |
| Storage Conditions | Store at -20°C protected from light. Lyophilized conjugates stable for over one year at -20°C. |
| Shelf Life | Stable for at least 12 months when stored at -20°C protected from light. |
| Package Specifications | 5 mg per vial; 10 mg per vial |
| Product Form | Yellow solid or powder |
| Key Features | Six distinct chemiluminescent labels with varied functional groups Types 0-3: acridinium esters with NHS active esters Types 4-5: acridinium sulfonamide salts with enhanced water solubility Type 6: acridinium hydrazide for aldehyde-reactive conjugation All variants >=98% purity with comparable luminescence performance Types 1-3: enhanced hydrolytic stability vs. type 0 Types 4-6: superior stability in acidic conditions (pH<4.8) |
| Purity | >=98% |
| Shipping Conditions | Ship at room temperature (20-25°C) within 48 hours; ship at -20°C for longer transit times |
| Appearance | Yellow solid or powder |
| Alias | Acridinium labels; Chemiluminescent labels |
| Safety | For research and diagnostic manufacturing use only. Store protected from light at -20°C. |
| Physical State | Solid |
| Grade | Chemiluminescent grade |
| Color | Yellow |
For research use only, not for clinical use.
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