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| Product Name | 90 µm High-Flow Strong Cation-Exchange Agarose Medium for High-Molecular-Weight Proteins |
| Catalog No. | IGM-HMM-0236 |
| Description | The Alta DiagnoTech strong cation-exchange chromatography medium uses high-flow, high-rigidity agarose beads with an open macroporous structure coupled with a sulfonate ligand. It is designed for biomolecule purification with high binding capacity, favorable pressure-flow behavior and straightforward cleaning-in-place. |
| Intended Use | Strong cation-exchange purification of high-molecular-weight proteins such as IgG, IgM and IgA. |
| Principle / Technology | Strong cation-exchange chromatography separates biomolecules according to surface-charge differences. |
| Performance Range / Specifications | 90 µm particles; 110-140 µmol/mL as H+ ion capacity; maximum operating pressure 0.3 MPa; designed for high-molecular-weight proteins with high volumetric throughput. |
| Storage Conditions | 20% ethanol at 4-30 °C |
| Package Specifications | 25 mL, 100 mL, 500 mL, 1 L, 5 L, 10 L and 50 L |
| Product Form | Agarose chromatography medium |
| Key Features | High binding capacity Favorable pressure-flow performance Scalable chromatography workflow Simple CIP cleaning and sanitization |
| Product Type | Ion-exchange chromatography medium |
| Function / Efficacy | Strong cation-exchange purification of high-molecular-weight proteins such as IgG, IgM and IgA. |
| Chromatography Mode | Strong cation-exchange |
| Matrix | High-flow, high-rigidity agarose beads with an open macroporous structure |
| Particle Size | 90 µm |
| Ligand / Bonded Phase | Sulfonate |
| Dynamic Binding Capacity | High dynamic binding capacity; no numerical value stated. |
| Ion Capacity | 110-140 µmol/mL as H+ |
| Maximum Operating Pressure | 0.3 MPa |
| CIP / Sanitization Conditions | 0.5 M NaOH |
| Recommended Flow Rate | 300-500 cm/h |
| Maximum Flow Rate | 700 cm/h at 0.1 MPa in a 26 mm ID × 15 cm bed column at 25 °C |
| pH Stability | pH 4-12 during operation; pH 3-14 during CIP |
| Chemical Stability | Common aqueous solutions, 6 M guanidine hydrochloride, 30% isopropanol and 70% ethanol. |
| Operating Temperature | 4-40 °C |
For research use only, not for clinical use.
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