65 µm Heparin Affinity Polymethacrylate Medium ~5 mg/mL Antithrombin III DBC
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65 µm Heparin Affinity Polymethacrylate Medium ~5 mg/mL Antithrombin III DBC

Cat.No: IGM-HMM-0259 Datasheet

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Product Name 65 µm Heparin Affinity Polymethacrylate Medium ~5 mg/mL Antithrombin III DBC
Catalog No. IGM-HMM-0259
Description The Alta DiagnoTech heparin affinity medium immobilizes high-purity heparin sodium on a polymethacrylate matrix. The polyanionic ligand interacts with antithrombin III, coagulation factors, lipoproteins, esterases, hormones and interferons while the hydrophilic bead surface limits nonspecific adsorption.
Intended Use Affinity purification of antithrombin III, coagulation factors, lipoproteins, esterases, hormones, interferons and other heparin-binding biomolecules.
Principle / Technology Heparin affinity chromatography using immobilized high-purity heparin sodium.
Performance Range / Specifications 65 µm particles; dynamic binding capacity approximately 5 mg/mL for antithrombin III; maximum pressure 0.8 MPa; recommended flow 100-500 cm/h.
Storage Conditions 20% ethanol at 4-25 °C
Package Specifications 30 mL, 100 mL, 500 mL, 1 L, 5 L, 10 L, 50 L and 100 L
Product Form Polymethacrylate heparin affinity chromatography medium
Key Features Approximately 5 mg/mL antithrombin III binding
High-purity heparin sodium ligand
Low ligand leakage and nonspecific adsorption
100-500 cm/h recommended flow
Product Type Heparin affinity chromatography medium
Function / Efficacy Affinity separation of heparin-binding proteins and biomolecules.
Chromatography Mode Heparin affinity chromatography
Matrix Polymethacrylate
Particle Size 65 µm
Ligand / Bonded Phase High-purity heparin sodium
Ligand Coupling Method Extended-spacer ligand coupling
Dynamic Binding Capacity Approximately 5 mg/mL for antithrombin III
Maximum Operating Pressure 0.8 MPa
CIP / Sanitization Conditions 2 M NaCl
Recommended Flow Rate 100-500 cm/h
pH Stability pH 4-12
Chemical Stability Stable in common aqueous buffers, 0.1 M NaOH, 0.05 M sodium acetate, 8 M urea, 6 M guanidine hydrochloride, nonionic detergents and 10% glycerol.
Operating Temperature 2-40 °C

For research use only, not for clinical use.

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