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| Product Name | 65 µm 1000 Å Strong Cation-Exchange PMMA Medium ~115 mg/mL IgG DBC |
| Catalog No. | IGM-HMM-0235 |
| Description | The Alta DiagnoTech strong cation-exchange chromatography medium uses hydrophilically modified PMMA beads carrying a sulfonate ligand. Monodisperse particles, broad pores and stable column-bed behavior support capture through polishing applications for biological samples. |
| Intended Use | Strong cation-exchange purification of charged biomolecules from capture through intermediate and polishing steps. |
| Principle / Technology | Strong cation-exchange chromatography using a sulfonate ligand on porous PMMA beads. |
| Performance Range / Specifications | Approximately 65 µm particles; approximately 1,000 Å pores; dynamic binding capacity approximately 115 mg/mL for IgG; ligand density 0.13 meq/mL; maximum pressure 0.5 MPa. |
| Package Specifications | 30 mL, 50 mL, 100 mL, 300 mL, 500 mL, 1 L, 5 L, 10 L, 50 L and 100 L |
| Product Form | PMMA ion-exchange chromatography medium |
| Key Features | ~115 mg/mL IgG dynamic binding capacity ~1,000 Å pore size Monodisperse 65 µm PMMA beads 150-750 cm/h recommended flow |
| Product Type | Strong cation-exchange chromatography medium |
| Function / Efficacy | Charge-based purification of biomolecules across capture, intermediate and polishing workflows. |
| Customization | Prepacked columns are available in 7.7 × 22 mm, 16 × 25 mm and 7.7 × 100 mm formats; additional formats may be customized. |
| Chromatography Mode | Strong cation-exchange chromatography |
| Matrix | Polymethyl methacrylate (PMMA) |
| Particle Size | Approximately 65 µm |
| Pore Size | Approximately 1,000 Å |
| Ligand / Bonded Phase | −(CH₂)₃SO₃− |
| Dynamic Binding Capacity | Approximately 115 mg/mL for IgG |
| Ligand Density | 0.13 meq/mL |
| Maximum Operating Pressure | 0.5 MPa |
| CIP / Sanitization Conditions | 0.5 M NaOH |
| Recommended Flow Rate | 150-750 cm/h |
| pH Stability | pH 2-12 |
| Chemical Stability | Common buffers, 1 M acetic acid, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride and 8 M urea; avoid strong oxidants |
For research use only, not for clinical use.
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