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| Product Name | 50-320 µm Crosslinked Dextran Gel-Filtration Media for Desalting and Buffer Exchange |
| Catalog No. | IGM-HMM-0251 |
| Description | The Alta DiagnoTech crosslinked dextran media are hydrophilic porous beads supplied in four swollen-particle grades. They provide gentle size-based separation for desalting, buffer exchange and removal of small molecules from viruses, proteins, polysaccharides and nucleic acids. |
| Intended Use | Desalting, buffer exchange, removal of small molecules and size-based purification of biomolecules, peptides, oligonucleotides, antibiotics, synthetic drugs and natural products. |
| Principle / Technology | Size-exclusion chromatography on crosslinked dextran beads. |
| Performance Range / Specifications | Four swollen-particle grades: 320, 140, 80 and 50 µm. Fractionation range 100-1,000 Da for linear molecules and 1,000-5,000 Da for globular molecules. Listed maximum flow rates for the four grades are 480, 100, 50 and 11 cm/h, respectively; separately specified flow-rate values are >480, >100, >47 and >11 cm/h. |
| Storage Conditions | 20% ethanol at 4-30 °C |
| Package Specifications | Each particle grade: 100 mL, 500 mL, 1 L and 10 L |
| Product Form | Crosslinked dextran gel-filtration medium |
| Key Features | Four swollen-particle grades from 50 to 320 µm 100-1,000 Da linear-molecule fractionation 1,000-5,000 Da globular-molecule fractionation Desalting and buffer-exchange applications |
| Product Type | Dextran size-exclusion chromatography medium |
| Function / Efficacy | Size-based desalting, buffer exchange and small-molecule removal. |
| Chromatography Mode | Size-exclusion chromatography |
| Matrix | Crosslinked dextran beads |
| Particle Size | 320, 140, 80 or 50 µm after swelling |
| Maximum Operating Pressure | 0.5 MPa |
| Recommended Flow Rate | >480, >100, >47 and >11 cm/h for the 320, 140, 80 and 50 µm grades, respectively |
| Maximum Flow Rate | 480, 100, 50 and 11 cm/h for the 320, 140, 80 and 50 µm grades, respectively |
| pH Stability | pH 2-13 |
| Chemical Stability | Common aqueous solutions, 1 M NaOH, 6 M guanidine hydrochloride, 30% isopropanol and 70% ethanol. |
| Operating Temperature | 4-40 °C |
For research use only, not for clinical use.
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