| Product Name | Oxazole Yellow/PI Membrane Permeability Apoptosis Detection Reagent |
| Catalog No. | CCAT-HMM-0016 |
| Description | Apoptosis refers to the genetically controlled, self-regulated, and orderly death of cells to maintain internal environmental stability. Apoptosis differs from necrosis; apoptosis generally refers to a programmed cell death process that occurs during cellular development or under certain factors through the regulation of intracellular genes and their products, while necrosis is a death process caused by strong physical, chemical, or biological factors leading to disordered cellular changes. The distinction between apoptosis and necrosis lies in characteristic morphological and biochemical changes, including alterations in cell membrane permeability and nuclear chromatin, cytoplasmic contraction, and loss of membrane asymmetry. |
| Application | This product can be used for membrane permeability apoptosis detection. |
| Spectral Parameters | Oxazole yellow dye: Ex/Em (nm) = 491/509 (with DNA); Propidium Iodine: Ex/Em (nm) = 535/617 (with DNA)） |
| Applicable Instruments | Flow cytometer, fluorescence microscope |
| Materials to Bring | 1 × PBS, pH 7.2-7.6; sterile ddH₂O |
| Storage | Store at 4°C away from light. |
| Features | Easy to use: Multiple types available, wide range of choices; Good stability: High fluorescence brightness and resistant to quenching; Good grouping effect: Clear grouping and strong specificity. |
| Notes | 1. Before use, centrifuge the product briefly to the bottom of the tube, then proceed with subsequent experiments. 2. Fluorescent dyes are susceptible to quenching. Please take care to avoid exposure to light to slow down fluorescence quenching. 3. For your safety and health, please wear a lab coat and disposable gloves when handling the product. |
For research use only, not for clinical use.
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