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| Product Name | Nasopharyngeal Specimen Preservation Medium, Inactivating |
| Catalog No. | ATR-SPS-0016 |
| Description | A guanidine-based inactivating transport medium that simultaneously preserves nucleic acids and inactivates infectious agents in nasopharyngeal specimens for safe transport and molecular diagnostic testing. |
| Intended Use | Collection, inactivation, and nucleic acid preservation of nasopharyngeal and oropharyngeal swab specimens for RT-PCR and other molecular diagnostic testing of respiratory pathogens. |
| Principle / Technology | Guanidinium thiocyanate denatures viral and bacterial proteins, inactivating infectious agents on contact while simultaneously lysing cells and stabilizing released nucleic acids through inhibition of endogenous nucleases. |
| Detection Method | PCR Ct value comparison with fresh specimens, viral inactivation validation by cell culture |
| Sample Type | Nasopharyngeal swabs, oropharyngeal swabs, nasal swabs, mid-turbinate swabs |
| Performance Range / Specifications | PCR Ct shift <1 compared to fresh specimen; complete inactivation of SARS-CoV-2, influenza, RSV within 5 minutes |
| Sensitivity / LOD | N/A |
| Specificity | N/A |
| Reaction Conditions / Protocol | Place swab into medium; break shaft; cap and mix by vortexing; specimen ready for direct PCR or extraction. |
| Components / Formulation | Guanidinium thiocyanate, Tris buffer, EDTA, non-ionic surfactant, nuclease-free water |
| Storage Conditions | 15–30°C |
| Shelf Life | 12 months |
| Package Specifications | 1.5 mL tubes (100/pack), 3 mL tubes (50/pack) |
| Product Form | Liquid in pre-filled tube |
| Quality Control | Viral inactivation validation, nuclease free, PCR inhibition testing, pH, sterility |
| Key Features | Inactivates pathogens for safe transport; compatible with direct PCR; nuclease free; ready to use; validated for respiratory pathogen panels |
For research use only, not for clinical use.
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