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| Product Name | Locke's Solution, pH 7.4 |
| Catalog No. | RERE-0441 |
| Description | Often written alongside Ringer solution as a close relative, Locke solution carries a slightly richer recipe for mammalian isolated experiments. Sodium chloride enters at 0.9 percent with potassium chloride at 0.042 percent, joined by calcium chloride and by glucose, whose addition distinguishes it from the carbohydrate-free Ringer base. Adjusted to pH 7.4, the fluid serves to perfuse the body or wash tissues while keeping excised preparations functioning normally throughout the recording or assay period. |
| Intended Use | Perfusion and tissue washing in mammalian isolated experiments, sustaining the normal physiological state of excised preparations. |
| Principle / Technology | Physiological concentrations of sodium, potassium and calcium chlorides plus glucose supply both the ionic milieu and an energy substrate that isolated mammalian tissue needs to remain viable. |
| Specificity | 0.9% sodium chloride; 0.042% potassium chloride; with calcium chloride and glucose; pH 7.4. |
| Reaction Conditions / Protocol | Maintain at the working temperature required by the preparation and perfuse or rinse tissues as the isolated-organ protocol directs. |
| Storage Conditions | 2-8°C; 6 months. |
| Package Specifications | 500 mL |
| Key Features | Glucose fortified relative to plain Ringer solution; pH held at 7.4; established mammalian isolated-organ medium. |
For research use only, not for clinical use.
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