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| Product Name | Glutamic-pyruvic Transaminase (GPT) Activity Assay Kit, 50T/24S |
| Catalog No. | AACAK-YJL-0019 |
| Detection Method | Visible spectrophotometry, Spectrophotometer |
| Storage | Store at 2-8°C, 6 months |
| Intended Use | For research use only. |
| Note | For your safety and health, please wear lab coat, disposable gloves and mask during operation. |
| Product Introduction | Glutamic-pyruvic transaminase (GPT), also known as alanine aminotransferase (ALT), catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate, producing pyruvate and glutamate. ALT is predominantly found in the liver cytosol, and its release into the bloodstream is a highly specific and sensitive indicator of hepatocellular damage. Measuring ALT activity is a cornerstone of liver function tests in both clinical diagnostics and preclinical toxicology studies. This kit employs a kinetic UV assay that monitors the oxidation of NADH coupled to the pyruvate produced by ALT. |
| Product Application | • Clinical and research assessment of liver health and hepatocellular injury. • Preclinical drug safety evaluation (hepatotoxicity screening). • Studies of liver diseases such as hepatitis, NAFLD/NASH, and cirrhosis. • Monitoring liver damage in models of ischemia-reperfusion or toxin exposure. |
| Product Advantages | • Kinetic Assay for Accuracy: Continuously monitors the reaction rate, providing superior accuracy over fixed-time endpoint methods and minimizing interference. • High Sensitivity: The coupled lactate dehydrogenase (LDH) reaction provides signal amplification, enabling detection of low levels of ALT activity. • Optimized for Serum/Plasma: Specifically formulated for direct use with clinical samples, requiring minimal sample volume and no complex pre-treatment. • Correlates with Standard Methods: Calibrated to deliver results consistent with international reference procedures (IFCC), ensuring data comparability. |
For research use only, not for clinical use.
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