- Home
- IVD
- By Technology Types
- By Diseases Types
- By Product Types
- Research
- Resource
- Distributors
- Company
Cat.No: SM-HMM-0003 Datasheet
Specification Quantities
| Product Name | SuperMag OH-500 nm |
| Catalog No. | SM-HMM-0003 |
| Description | Silicon dioxide series magnetic microspheres are specially designed for nucleic acid extraction and purification. The surface is silica material, modified with a large number of OH or COOH groups, and can bind to nucleic acids in solution through hydrophobic, hydrogen bonding and electrostatic interaction under high salt and low pH conditions, without binding with other impurities (such as proteins), and quickly separate nucleic acids from biological samples. The operation is safe and simple, which is conducive to the automation and high throughput extraction of nucleic acid. |
| Features | Strong nucleic acid binding capacity: >20 µg DNA/mg magnetic beads;
Good operation performance: uniform dispersion of magnetic beads, super paramagnetic, magnetic response time <30s; Complete silicon oxide layer coating, stable performance in use. |
| Storage | Stable at 2-8°C (can be stored or transported at room temperature for short periods of time) |
| Shelf Life | 2 years |
| Average Particle Size | 300-500 nm |
| Shell | SiO2 |
| Appearance | Monodisperse |
| Preservation Fluid | 20% ethanol |
| Concentration | 10 mg/mL、50 mg/mL |
| Applications | PCR product purification; Plasmid extraction; Viral nucleic acid extraction; Genomic DNA extraction from blood, tissue, plant and microbial samples. |
• The SuperMag OH 500 nm magnetic particles are engineered as a high-performance tool for research applications, particularly in biotechnology, molecular biology, and diagnostic assay development. These particles are designed to facilitate efficient separation, purification, and immobilization of biomolecules, such as proteins, nucleic acids, or antibodies, through magnetic-based techniques.
• Magnetic particles have revolutionized laboratory workflows by replacing traditional centrifugation or filtration methods, offering faster processing times and reduced sample loss. The 500 nm size of these particles strikes an optimal balance between high surface area for biomolecule binding and ease of magnetic manipulation, making them versatile for various research protocols.
• Researchers commonly use these particles in applications like immunoprecipitation, cell sorting, nucleic acid extraction, and enzyme immobilization. Their compatibility with automated platforms further enhances their utility in high-throughput screening and diagnostic kit development.
• The SuperMag OH 500 nm particles are manufactured using advanced chemical synthesis methods to ensure uniform size distribution, high monodispersity, and robust surface chemistry, which are critical for reproducible and reliable results in research settings.
• Uniform Particle Size: The 500 nm diameter ensures consistent performance across experiments, minimizing variability in binding efficiency and magnetic response.
• High Surface Area: The spherical shape and size provide ample surface area for immobilizing biomolecules, enhancing capture capacity and sensitivity in assays.
• Superparamagnetic Properties: These particles exhibit strong magnetic responsiveness when exposed to an external field but show no residual magnetism once the field is removed, preventing aggregation and simplifying resuspension.
• Surface Functionalization: The particles are coated with hydroxyl (-OH) groups, enabling easy conjugation with biomolecules or chemical linkers through standard coupling chemistries like EDC/NHS or glutaraldehyde activation.
• Compatibility with Diverse Buffers: They maintain stability and functionality across a wide range of pH and ionic strength conditions, supporting flexibility in experimental design.
• Enhanced Efficiency: The magnetic separation process reduces hands-on time and eliminates the need for centrifugation, streamlining workflows in high-throughput research environments.
• Reproducibility: Uniform particle size and consistent surface chemistry ensure reliable results across batches and experiments, critical for validating research findings.
• Scalability: The particles can be easily scaled up for large-volume sample processing without compromising performance, supporting industrial or clinical research applications.
• Versatility: Their hydroxyl surface allows for customization with various biomolecules, making them adaptable to diverse research needs, from protein purification to diagnostic assay development.
• Cost-Effectiveness: By improving yield and reducing sample loss, these particles help lower overall research costs while maintaining high-quality data output.
For research use only, not for clinical use.
|
There is no product in your cart. |