Magnetic Nanoparticles (400 nm)

Magnetic Nanoparticles (MNPs) have emerged as a pivotal class of nanomaterials in modern scientific research, with rapid development and expanding application value over the past few decades. These nanoscale particles, typically composed of magnetic metal oxides, stand out for their unique integration of nanoscale properties and magnetic responsiveness—two features that make them indispensable tools across multiple scientific disciplines.
Among the various materials used to fabricate MNPs, iron oxide (especially Fe₃O₄, magnetite) has become the gold standard for research applications. This is primarily due to its superior biocompatibility compared to other magnetic materials like cobalt or nickel (which exhibit inherent biological toxicity) and its status as one of the most magnetically robust natural minerals on Earth. For research scenarios—where safety, stability, and reproducibility are non-negotiable—Fe₃O₄-based MNPs eliminate the risk of toxic leaching while maintaining reliable magnetic performance, making them ideal for experiments involving biological samples (such as cells, proteins, or nucleic acids).
The 400 nm size of our Magnetic Nanoparticles is a carefully selected parameter tailored to research needs. In the spectrum of MNPs (which typically range from 1 nm to several micrometers), 400 nm balances two critical requirements: sufficient magnetic strength for efficient separation and manipulation, and a size that avoids interference with biological or chemical processes under study. For example, smaller MNPs (e.g., <100 nm) may lack the magnetic responsiveness needed for rapid separation in large-volume samples, while larger microscale magnetic beads (e.g., >1 μm) can disrupt cell cultures or block microfluidic channels—limitations that the 400 nm size overcomes.
In recent years, the demand for 400 nm Fe₃O₄-based MNPs in research has surged, driven by their versatility across key research areas. They serve as foundational tools in magnetic resonance imaging (MRI) research, where they enhance signal contrast to visualize cellular or tissue-level structures; in magnetic separation experiments, where they enable the purification of target molecules (e.g., DNA, RNA, proteins) or cells from complex mixtures; in targeted drug delivery studies, where they are used to simulate site-specific drug transport under external magnetic guidance; and in tumor thermotherapy research, where they generate heat in response to alternating magnetic fields to explore selective cancer cell ablation mechanisms. Additionally, they find applications in catalytic research (as recyclable catalyst carriers) and environmental science studies (as adsorbents for heavy metal removal from water samples).
Our 400 nm Magnetic Nanoparticles (Cat. No.: SM-HMM-0071) builds on this established background, with a Fe₃O₄ magnetic core and a stable, sterile water-based preservation system. It is engineered to meet the rigorous standards of research use—ensuring batch-to-batch consistency, non-toxicity, and compatibility with common laboratory protocols—making it a reliable choice for researchers in biochemistry, cell biology, materials science, and environmental science.