- Home
- IVD
- By Technology Types
- By Diseases Types
- By Product Types
- Research
- Resource
- Distributors
- Company
| Product Name | Magnetic Nanoparticle-Based Nucleic Acid Delivery Reagent |
| Catalog No. | ATR-CTR-0013 |
| Description | A magnetically assisted transfection system using cationic polymer-coated iron oxide nanoparticles that are concentrated onto the cell surface by an external magnetic field, dramatically increasing nucleic acid delivery efficiency. |
| Intended Use | Enhanced delivery of plasmid DNA, siRNA, and antisense oligonucleotides into adherent and suspension cells; particularly effective for low-volume and high-throughput transfection in multi-well plate formats. |
| Principle / Technology | Cationic polymer-coated superparamagnetic iron oxide nanoparticles complex nucleic acids; application of a magnetic plate beneath the culture vessel concentrates the nanoparticles onto the cell monolayer within minutes, increasing the local DNA concentration at the cell surface and enhancing uptake. |
| Detection Method | Reporter gene expression, magnetic field effect on transfection efficiency (with vs without magnet comparison) |
| Sample Type | Adherent cell lines in multi-well plates, suspension cells, primary cells, difficult-to-transfect lines |
| Performance Range / Specifications | Transfection efficiency enhancement 5–20 fold compared to standard lipid transfection without magnetic assistance; transfection complete within 15–30 minutes incubation on magnetic plate |
| Sensitivity / LOD | N/A |
| Specificity | N/A |
| Reaction Conditions / Protocol | Mix DNA with magnetic nanoparticle reagent; incubate 20 min for complex formation; add to cells; place culture plate on magnetic plate for 15–30 min; remove magnetic plate; continue culture; assay 24–48 hours. |
| Components / Formulation | Cationic polymer-coated iron oxide nanoparticles, 1 mg/mL in water, sterile, magnetic plate (96-well or 24-well format) |
| Storage Conditions | 2–8°C; do not freeze; protect from magnetic fields |
| Shelf Life | 12 months |
| Package Specifications | 100 µL reagent (for 100 transfections in 96-well) + magnetic plate |
| Product Form | Liquid nanoparticle suspension with magnetic plate |
| Quality Control | Particle size <100 nm by DLS, zeta potential +20 to +40 mV, sterility, endotoxin <0.5 EU/mL, transfection enhancement validation |
| Key Features | Magnetically enhanced delivery; reduced transfection time; increased efficiency; low cytotoxicity; compatible with multi-well formats; DNA dose reduction possible |
For research use only, not for clinical use.
|
There is no product in your cart. |
Copyright © 2026 Alta DiagnoTech. All rights reserved.
