Glycosylated Hemoglobin (GHb) Content Assay Kit, 50T/48S

Glycosylated Hemoglobin (GHb), also known as glycated hemoglobin, is a critical biological marker formed through a non-enzymatic reaction between glucose in the serum and hemoglobin in erythrocytes. This reaction is slow, continuous, and irreversible, meaning the amount of GHb produced is directly proportional to the average blood glucose level in the 8–12 weeks prior to testing—unlike single-point blood glucose measurements, which only reflect instantaneous glucose levels.
GHb is not a single component but a group of glycated hemoglobin subtypes, including HbA1a, HbA1b, and HbA1c. Among these, HbA1c accounts for approximately 70% of total GHb and has a relatively stable structure, making it the most widely recognized and utilized subtype for clinical and research purposes.
In the field of diabetes research, GHb plays an indispensable role. It serves as a gold standard for evaluating long-term blood glucose control in diabetes models (such as rodent or other animal models used in preclinical studies), as it can effectively reflect whether blood glucose has been stably managed over an extended period (typically 4–10 weeks). For researchers studying diabetes pathogenesis, treatment efficacy, or complications (e.g., peripheral vascular and cardiovascular complications associated with poor long-term glucose control), accurate measurement of GHb content is essential to assess the success of experimental interventions—whether testing new drugs, dietary modifications, or other therapeutic strategies.
This GHb Content Assay Kit is designed specifically to meet the needs of research laboratories, enabling precise quantification of GHb in biological samples (such as animal whole blood or erythrocyte samples). It leverages visible spectrophotometry, a well-established and reliable analytical method, to ensure consistent and reproducible results that support robust research outcomes.