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| Product Name | Glycogen Synthase (GCS) Activity Assay Kit, 100T/96S |
| Catalog No. | SCAK-YJL-0151 |
| Detection Method | Micro-volume method, Spectrophotometer/Microplate Reader |
| Storage | Store at -20°C, 6 months |
| Intended Use | For research use only. |
| Note | For your safety and health, please wear lab coat, disposable gloves and mask during operation. |
Glycogen Synthase (GCS) is a rate-limiting enzyme critical to glycogenesis, the biological process of converting glucose into glycogen for cellular energy storage. It catalyzes the transfer of glycosyl groups from uridine diphosphate glucose (UDPG) to the non-reducing end of glycogen primers, forming α-1,4 glycosidic bonds to extend glycogen chains. This enzymatic activity is tightly linked to glucose metabolism and blood glucose homeostasis, making it a key target for studying metabolic pathways.In research settings, understanding GCS activity is essential for investigating conditions associated with glucose regulation disorders, such as diabetes, insulin resistance, and glycogen storage diseases. Abnormal GCS activity can disrupt glycogen synthesis, leading to impaired energy storage in tissues like the liver and muscles—organs where glycogen plays a vital role in maintaining energy balance.The Glycogen Synthase (GCS) Activity Assay Kit is designed to quantify GCS activity in biological samples, enabling researchers to evaluate how factors like drugs, hormones, or genetic modifications affect this enzyme. By providing accurate measurements of GCS activity, the kit supports studies in biochemistry, molecular biology, and metabolic research, laying the groundwork for developing therapeutic strategies for metabolic diseases.This kit is exclusively for research use and not intended for clinical diagnosis or human use. It is optimized to work with common biological samples, including animal tissue extracts, cell lysates, and purified enzymes, meeting the diverse needs of laboratory research.
Utilizes a micro-volume detection method compatible with spectrophotometers or microplate readers, ensuring flexibility for different laboratory equipment setups.
Offers a storage period of 6 months when stored at -20°C, providing long-term usability for research projects with extended timelines.
Enables accurate quantification of GCS activity by detecting reaction products (e.g., changes in NADH levels or colored/fluorescent signals) that correlate directly with enzyme activity.
Supports analysis of multiple sample types, including tissue extracts, cell lysates, and purified GCS enzymes, adapting to various research models (e.g., animal, cellular, bacterial studies).
Includes essential reagents to create a stable reaction environment—such as GCS enzyme reaction buffers (maintaining optimal pH and ion strength), UDPG (substrate), and glycogen primers—ensuring reliable enzymatic reactions.
Delivers precise and reproducible results, which is critical for research experiments requiring consistent data to validate hypotheses about GCS function and metabolic pathways.
Simplifies the assay workflow with pre-formulated reagents, reducing the time and effort spent on reagent preparation and minimizing the risk of human error in experimental setup.
Has broad sample compatibility, eliminating the need for specialized sample processing kits and allowing researchers to test different sample types without switching assay systems.
Ensures long-term reagent stability (6 months at -20°C), reducing the frequency of kit reordering and supporting continuous research without interruptions due to reagent expiration.
Aligns with key research priorities in metabolic science, addressing the demand for tools to study glucose metabolism and related disorders—making it a relevant and valuable asset for research labs.
For research use only, not for clinical use.
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