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| Product Name | UDP-Glucuronosyltransferase (UDPGT) Activity Assay Kit, 100T/48S |
| Catalog No. | SCAK-YJL-0226 |
| Detection Method | Micro-volume method |
| Storage | Store at -20°C, 6 months |
| Intended Use | For research use only. |
| Note | For your safety and health, please wear lab coat, disposable gloves and mask during operation. |
• UDP-glucuronosyltransferases (UGTs) are a superfamily of enzymes critical for the Phase II metabolic detoxification process in humans and animals. These enzymes catalyze the conjugation of glucuronic acid to a wide range of endogenous and exogenous substrates, including drugs, hormones, and environmental toxins, facilitating their excretion via bile or urine.
• UGTs play a pivotal role in drug metabolism, influencing pharmacokinetics, drug efficacy, and toxicity. Variations in UGT activity can lead to interindividual differences in drug response, making their study essential for personalized medicine and drug development.
• The UDP-Glucuronosyltransferase (UGT) Activity Assay Kit is designed to quantify UGT enzyme activity in biological samples, such as liver microsomes, cell lysates, or tissue homogenates. This enables researchers to evaluate metabolic pathways, screen for UGT inhibitors or inducers, and assess species-specific differences in drug metabolism.
• This kit supports studies in pharmacology, toxicology, biochemistry, and molecular biology, providing a reliable tool for understanding UGT-mediated biotransformation and its implications in health and disease.
• High Sensitivity: Detects low levels of UGT activity with high precision, ensuring accurate results even in samples with minimal enzyme expression.
• Broad Compatibility: Works with a variety of sample types, including human, animal, and recombinant UGT sources, enabling cross-species comparisons.
• User-Friendly Protocol: The assay requires minimal hands-on time and includes all necessary reagents, reducing setup complexity and potential errors.
• Colorimetric Detection: Utilizes a simple colorimetric readout, eliminating the need for specialized equipment like HPLC or mass spectrometry.
• Stable Reagents: All components are provided in a lyophilized format with long shelf lives, ensuring consistency and reducing waste.
• Time-Efficient: The streamlined protocol allows for rapid data acquisition, enabling high-throughput screening in drug discovery workflows.
• Cost-Effective: Compared to alternative methods, this kit offers a lower cost per sample without compromising on quality or reliability.
• Flexible Application: Suitable for both basic research and industrial applications, including drug metabolism studies, enzyme characterization, and inhibitor screening.
• Reproducible Results: High intra- and inter-assay precision ensures consistent performance across multiple experiments and user groups.
• Comprehensive Support: Detailed documentation and technical support are available to assist users at every step, from protocol optimization to data interpretation.
For research use only, not for clinical use.
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