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| Product Name | FITC-Dextran Sulfate, 10 kDa |
| Catalog No. | RERE-0132 |
| Description | Fluorescein isothiocyanate-labelled dextran sulfate with a nominal molecular weight of 10 kDa, a small-enough fraction to move across permeable barriers while remaining too large for passive diffusion through intact endothelium. The fluorescein label permits direct reading by fluorescence microscopy, plate reader or flow cytometry, and the sulfate groups alter charge and binding behaviour relative to neutral FITC-dextran. Typical applications include permeability and leakage assays, tracer studies of barrier function and clearance experiments. |
| Intended Use | Fluorescent tracing of permeability, barrier leakage and solute distribution |
| Principle / Technology | Fluorescein labelling enables direct fluorescence detection of the dextran fraction at tracer sites |
| Sample Type | Vascular permeability models, barrier function assays and tracer clearance studies |
| Specificity | Nominal 10 kDa; fluorescein-labelled sulfated dextran |
| Reaction Conditions / Protocol | Dissolve under light-protected conditions and administer or apply at the assay concentration |
| Storage Conditions | Protect from light; -20°C; under argon |
| Package Specifications | 50 mg; 100 mg; 250 mg; 500 mg; 1 g |
| Key Features | Low-molecular-weight fraction for permeable-barrier studies; strong fluorescein signal |
| Readouts / Downstream Assays | Fluorescein excitation/emission by microscope, plate reader or flow cytometer |
For research use only, not for clinical use.
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