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| Product Name | FITC-Dextran, 250 kDa |
| Catalog No. | RERE-0146 |
| Description | A high-molecular-weight FITC-dextran tracer whose 250 kDa dextran core restricts passage to pathways that admit very large macromolecules. This size class sits between the common 70 kDa and 2000 kDa grades, offering intermediate vascular retention for barrier-integrity work in tumour vasculature, inflammation and edema models, and for testing the macromolecule sieving properties of engineered membranes and hydrogels. Signal develops on standard FITC channels with the low background expected of dextran-based probes. |
| Intended Use | Vascular barrier integrity, macromolecular leak and membrane sieving assays needing an intermediate large tracer |
| Principle / Technology | Fluorescein-tagged 250 kDa dextran crosses only high-permeability routes; fluorescence quantifies leakage or retention |
| Sample Type | Plasma, tissue homogenates and perfusates from tracer-dosed models |
| Specificity | Molecular weight 250 kDa; FITC-labelled dextran; read on FITC channels (Ex/Em about 490/520 nm) |
| Reaction Conditions / Protocol | Introduce the tracer systemically or into the donor compartment, then quantify fluorescence in receiver samples against a standard curve |
| Storage Conditions | 2 to 8°C |
| Package Specifications | 25 mg; 100 mg |
| Key Features | Intermediate-large tracer size between 70 kDa and 2000 kDa grades; stable fluorescence; low tissue binding |
| Readouts / Downstream Assays | FITC-channel fluorescence (Ex/Em about 490/520 nm) |
For research use only, not for clinical use.
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