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| Product Name | FITC-Dextran, 10 kDa |
| Catalog No. | RERE-0145 |
| Description | The lowest molecular weight grade of the FITC-dextran tracer family, conjugating fluorescein isothiocyanate to a 10 kDa dextran backbone. Its compact hydrodynamic size lets it pass through paracellular routes and fenestrated endothelium more readily than larger grades, making it a standard probe for intestinal permeability measurements, tight-junction leak assays and microvascular leakage models where small-tracer flux is the readout. Fluorescence is read on standard FITC channels, and the dextran carrier resists nonspecific tissue binding. |
| Intended Use | Paracellular permeability, tight-junction leak and microvascular flux assays favouring a small tracer |
| Principle / Technology | Fluorescein-labelled dextran traverses size-selective barriers; fluorescence intensity quantifies tracer passage |
| Sample Type | Plasma, urine, intestinal lavage and tissue perfusates from tracer-dosed models |
| Specificity | Molecular weight 10 kDa; FITC-labelled dextran; read on FITC channels (Ex/Em about 490/520 nm) |
| Reaction Conditions / Protocol | Administer or apply the tracer, collect the recipient compartment at defined intervals and quantify fluorescence against a standard curve |
| Storage Conditions | 2 to 8°C |
| Package Specifications | 100 mg; 500 mg; 1 g |
| Key Features | Smallest grade in the FITC-dextran range; sharp paracellular flux resolution; low nonspecific binding |
| Readouts / Downstream Assays | FITC-channel fluorescence (Ex/Em about 490/520 nm) |
For research use only, not for clinical use.
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