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| Product Name | DNA Decontamination Reagent, Liquid Concentrate |
| Catalog No. | ATRCS-0008 |
| Description | A concentrated chemical decontamination solution based on DNA intercalating and cleaving chemistry for the permanent removal of amplifiable DNA from laboratory equipment and surfaces in molecular biology facilities. |
| Intended Use | Eliminating contaminating DNA from equipment used in forensic DNA analysis, ancient DNA studies, single-cell genomics, and other applications where even trace DNA contamination generates false results. |
| Principle / Technology | Copper-phenanthroline or similar redox-active complex generates reactive oxygen species that cleave DNA phosphodiester backbone; surfactant formulation ensures surface penetration. |
| Detection Method | qPCR with broad-range 16S or Alu primers, negative control amplification in treated work areas |
| Sample Type | Forensic lab equipment, micromanipulators, flow cytometry sorters, single-cell isolation platforms |
| Performance Range / Specifications | >99.9% reduction in amplifiable DNA; NTC Ct values >40 cycles |
| Sensitivity / LOD | N/A |
| Specificity | Specific for DNA; does not degrade proteins or RNA significantly |
| Reaction Conditions / Protocol | Dilute 1:10 with water; apply to clean surface; incubate 10–15 minutes; wipe or rinse with nuclease-free water. |
| Components / Formulation | Copper(II) sulfate, 1,10-phenanthroline, 3-mercaptopropionic acid, surfactant, stabilizer |
| Storage Conditions | 2–8°C, protect from light |
| Shelf Life | 6 months after dilution |
| Package Specifications | 50 mL concentrate (makes 500 mL), 100 mL concentrate |
| Product Form | Liquid concentrate |
| Quality Control | DNA degradation efficiency validation by qPCR, lot release testing against genomic and plasmid DNA targets |
| Key Features | High efficiency DNA degradation; works on dried DNA residues; suitable for sensitive forensic and single-cell applications; non-enzymatic mechanism |
For research use only, not for clinical use.
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