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| Product Name | Cerebrospinal Fluid Specimen Stabilizer and Diluent |
| Catalog No. | ATRD-0010 |
| Description | A protein-supplemented buffer solution specifically formulated to stabilize labile protein biomarkers in cerebrospinal fluid during specimen handling, dilution, and storage prior to neurological biomarker analysis. |
| Intended Use | Dilution and short-term stabilization of CSF specimens for measurement of amyloid-beta, tau protein, neurofilament light chain, and other neurodegenerative disease biomarkers. |
| Principle / Technology | BSA and casein provide protective carrier proteins; EDTA chelates divalent cations that activate metalloproteinases; aprotinin inhibits serine proteases that degrade peptide biomarkers. |
| Detection Method | CSF biomarker stability measured by ELISA over 24 hours at 4°C versus baseline |
| Sample Type | Human lumbar CSF, ventricular CSF |
| Performance Range / Specifications | Biomarker recovery >90% after 24 hours at 4°C; protease activity undetectable |
| Sensitivity / LOD | N/A |
| Specificity | N/A |
| Reaction Conditions / Protocol | Dilute CSF 1:2 to 1:10; mix gently; use within 4 hours at room temperature or 24 hours at 4°C. |
| Components / Formulation | PBS pH 7.4, BSA 0.5%, EDTA, aprotinin, sodium azide 0.02% |
| Storage Conditions | 2–8°C |
| Shelf Life | 6 months |
| Package Specifications | 50 mL, 100 mL |
| Product Form | Liquid, ready to use |
| Quality Control | Protease inhibitor activity verification, protein stabilization validation, sterility |
| Key Features | Protease inhibitor fortified; designed for neurodegenerative biomarkers; ready to use; validated for amyloid-beta and tau assays |
For research use only, not for clinical use.
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