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| Product Name | 50 µm 1500 Å Strong Anion-Exchange PS-DVB Medium ~120 mg/mL BSA DBC |
| Catalog No. | IGM-HMM-0255 |
| Description | The Alta DiagnoTech strong anion-exchange medium uses monodisperse PS-DVB beads with an open macroporous structure. Hydrophilic surface modification reduces nonspecific adsorption, while a quaternary-ammonium ligand provides high-capacity charge-based separation with high mechanical strength. |
| Intended Use | Large-scale purification of monoclonal antibodies, viruses, vaccines and high-molecular-weight recombinant proteins. |
| Principle / Technology | Strong anion-exchange chromatography using a quaternary-ammonium ligand on macroporous PS-DVB beads. |
| Performance Range / Specifications | 50 µm particles; 1,500 Å pores; ligand density approximately 0.25 meq/mL; dynamic binding capacity approximately 120 mg/mL for BSA; maximum pressure 2.0 MPa. |
| Package Specifications | 30 mL, 50 mL, 100 mL, 300 mL, 500 mL, 1 L, 5 L, 10 L, 50 L and 100 L |
| Product Form | PS-DVB strong anion-exchange chromatography medium |
| Key Features | Approximately 120 mg/mL BSA dynamic binding capacity 1,500 Å open macropores 2.0 MPa maximum pressure pH 1-14 stability |
| Product Type | Strong anion-exchange chromatography medium |
| Function / Efficacy | High-capacity charge-based purification of negatively charged biomolecules. |
| Customization | Prepacked columns are available in 7.7 × 22 mm, 16 × 25 mm and 7.7 × 100 mm formats; additional formats may be customized. |
| Functional Group | Quaternary ammonium |
| Chromatography Mode | Strong anion-exchange chromatography |
| Matrix | Polystyrene-divinylbenzene (PS-DVB) |
| Particle Size | 50 µm |
| Pore Size | 1,500 Å |
| Ligand / Bonded Phase | −CH₂N⁺(CH₃)₃ |
| Dynamic Binding Capacity | Approximately 120 mg/mL for BSA |
| Ligand Density | Approximately 0.25 meq/mL |
| Maximum Operating Pressure | 2.0 MPa |
| CIP / Sanitization Conditions | 1 M NaOH |
| Recommended Flow Rate | 50-300 cm/h |
| pH Stability | pH 1-14 |
| Chemical Stability | Common buffers, 1 M acetic acid, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropanol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride and 8 M urea. Avoid strong oxidants, oxidizing acids, strong reducing agents, acetone and benzyl alcohol. |
| Operating Temperature | 4-30 °C |
For research use only, not for clinical use.
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