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| Product Name | Sialic Acid Content Assay Kit, 50T/48S |
| Catalog No. | SCAK-YJL-0020 |
| Detection Method | Visible spectrophotometry, Spectrophotometer |
| Storage | Store at -20°C, 6 months |
| Intended Use | For research use only. |
| Note | For your safety and health, please wear lab coat, disposable gloves and mask during operation. |
| Product Introduction | Sialic acids are a family of nine-carbon sugars typically found at the terminal positions of glycoproteins and glycolipids on cell surfaces and in secretions. They play crucial roles in cell-cell interaction, immune recognition, protein stability, and pathogen attachment. Altered sialylation is a hallmark of cancer, inflammation, and genetic disorders. This kit is based on the classic periodate-resorcinol method, which specifically reacts with sialic acids to generate a purple chromophore, allowing for sensitive quantification in serum, biological fluids, or purified glycoconjugate samples. |
| Product Application | • Analysis of serum sialic acid as a potential inflammatory or cancer biomarker. • Glycoprotein characterization during biopharmaceutical development and quality control. • Research on host-pathogen interactions and viral hemagglutinin receptors. • Studies of sialylation in neural development, immune regulation, and genetic diseases like sialuria. |
| Product Advantages | • Classic, Validated Method: Employs the well-established periodate-resorcinol reaction known for its reliability and specificity for sialic acids. • No Need for Prior Hydrolysis: The kit efficiently releases bound sialic acids, simplifying the workflow compared to methods requiring separate hydrolysis steps. • Suitable for Complex Matrices: Works effectively with direct serum samples and various biological fluids. • Clear Quantitative Results: Produces a stable color with a strong absorbance signal for confident quantification. |
For research use only, not for clinical use.
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