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| Product Name | PIPES sesquisodium salt biological buffer, CAS 100037-69-2, pH range 6.1-7.5 |
| Catalog No. | ATR-B-YJL-0264 |
| Description | PIPES-1.5Na, the sesquisodium salt of piperazine-N,N'-bis(2-ethanesulfonic acid), is widely used in protein and enzyme research, with an effective buffering range of pH 6.1-7.5. It is a zwitterionic buffer, meaning it carries both positive and negative charges within its buffering pH range. Owing to its relatively low cost and high solubility, it is often regarded as an alternative to HEPES or MES. It is frequently employed in biological research to maintain pH and preserve the activity of proteins and enzymes. |
| Intended Use | Used as a biological buffer in protein and enzyme research and other life science applications requiring stable pH within 6.1-7.5. |
| Principle / Technology | As a zwitterionic buffer, PIPES-1.5Na maintains a stable pH within its buffering range while carrying both positive and negative charges. Proper buffering conditions keep the pH and temperature stable without inducing ionization effects that could alter protein structure or function. |
| Package Specifications | 25 kg/drum |
| Key Features | Effective buffering range of pH 6.1-7.5 Zwitterionic buffer carrying both positive and negative charges within its pH range Low cost and high solubility Commonly used as an alternative to HEPES or MES Maintains pH and preserves protein and enzyme activity in biological research |
| Purity | >99% |
| pH Range / Optimal pH | pH 6.1-7.5 |
| Application Notes / Precautions | Use at an appropriate concentration under correct buffering conditions: maintain stable pH, keep the temperature constant, and avoid inducing ionization that could affect protein structure and function. Note that PIPES-1.5Na is more temperature-sensitive than many other buffers, and its buffering performance can be affected by temperature changes. |
| Alias | PIPES sesquisodium salt; PIPES-1.5Na |
| CAS Number | 100037-69-2 |
| Other Name | Piperazine-N,N'-bis(2-ethanesulfonic acid) sesquisodium salt |
| Working Concentration | 10-100 mM for most biological research applications |
For research use only, not for clinical use.
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