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| Product Name | Mouse CCKAR (Cholecystokinin A Receptor) ELISA Kit |
| Catalog No. | HTK-YJL-0356 |
| Synonyms | Cholecystokinin Receptor Type A ELISA Kit, CCK-A Receptor ELISA Kit, CCK-AR ELISA Kit, Cholecystokinin-1 Receptor ELISA Kit, CCK1-R ELISA Kit, CCKAR ELISA Kit, CCKRA ELISA Kit |
| Species | Mouse |
| UniProt ID | O08786 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antibody |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 0.156-10 ng/ml |
| Sensitivity | 0.094 ng/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with CCKAR, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
Cholecystokinin A Receptor (CCKAR), also known as CCK-1 Receptor, is a key G protein-coupled receptor (GPCR) involved in mediating the biological effects of cholecystokinin (CCK), a critical gut-brain peptide. It plays essential roles in multiple physiological processes, including gastrointestinal motility regulation, pancreatic enzyme secretion, gallbladder contraction, and the modulation of appetite and energy metabolism.
In preclinical research, mouse models are widely used to study the function and mechanism of CCKAR due to their genetic similarity to humans and the availability of well-established experimental systems. Abnormal expression or dysfunction of CCKAR has been linked to various pathological conditions, such as obesity, diabetes, gastrointestinal disorders, and certain neurological diseases, making it a valuable target for basic research and drug discovery.
The Mouse CCKAR ELISA Kit is designed to quantitatively detect CCKAR levels in biological samples, providing researchers with a reliable tool to explore the role of CCKAR in disease progression, drug efficacy evaluation, and molecular biology studies. Its development meets the growing demand for accurate and efficient detection methods in translational research and preclinical studies.
Species-specific design: Exclusively optimized for detecting CCKAR in mouse samples, ensuring high compatibility with mouse-derived serum, plasma, cell culture supernatants, and tissue/cell lysates.
Sandwich ELISA technology: Utilizes double antibody sandwich method to enhance detection specificity and reduce non-specific binding, enabling precise quantification of target proteins.
Wide dynamic range: Covers a detection range of 0.156-10 ng/ml, accommodating both low and high expression levels of CCKAR in various sample types.
High sensitivity: Achieves a detection limit of 0.094 ng/ml, allowing for the detection of trace amounts of CCKAR in samples with low concentrations.
Short reaction duration: Completes the entire detection process within 4 hours, improving experimental efficiency and reducing waiting time for results.
Stable storage conditions: Can be stored at 2-8°C (sealed) without cryopreservation, simplifying inventory management and reducing product degradation risks.
Exceptional specificity: Specifically binds to mouse CCKAR with no obvious cross-reactivity with other CCK receptor subtypes or homologous proteins, ensuring accurate and reliable test results.
Quantitative accuracy: Provides precise numerical data on CCKAR concentrations, facilitating statistical analysis and comparison between different experimental groups.
User-friendly operation: Follows standard ELISA protocols, requiring no specialized equipment or advanced technical skills, suitable for both experienced researchers and laboratory beginners.
Versatile sample compatibility: Compatible with multiple common biological sample types, eliminating the need for complex sample preprocessing and expanding experimental application scenarios.
Consistent performance: Undergoes strict quality control during production, ensuring batch-to-batch reproducibility and minimizing experimental variability.
Research-focused design: Tailored for academic research and preclinical studies, aligning with the core needs of life science, pharmacology, and medical research projects.
For research use only, not for clinical use.
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