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| Product Name | Library Fragment-Selection Buffer |
| Catalog No. | ATR-B-YJL-0205 |
| Description | A magnetic-bead cleanup buffer formulated to remove short primer-dimer and adapter-dimer products while retaining target library fragments. |
| Intended Use | DNA library preparation, RNA library preparation and multiplex amplicon cleanup. |
| Principle / Technology | The buffer changes the interaction strength between nucleic acid fragments and purification beads, allowing short dimer products to be washed away while target fragments remain captured. |
| Detection Method | Downstream fragment analysis, library quantification and sequencing. |
| Sample Type | Amplified DNA libraries, RNA-derived libraries and multiplex PCR products. |
| Performance Range / Specifications | 2.5 mL or 10 mL; designed to use a consistent dilution ratio across cleanup workflows. |
| Specificity | Preferentially removes short dimer products without materially reducing target yield or library uniformity. |
| Reaction Conditions / Protocol | Use with compatible magnetic purification beads during post-amplification or library-cleanup steps according to the validated bead-to-sample ratio. |
| Components / Formulation | Ready-to-use fragment-selection buffer for magnetic-bead purification. |
| Package Specifications | 2.5 mL; 10 mL. |
| Product Form | Liquid magnetic-bead cleanup buffer. |
| Quality Control | Dimer removal, target recovery, library uniformity and multiplex-product uniformity are evaluated. |
| Key Features | Effective dimer removal; retained target yield; preserved library uniformity; simplified dilution workflow. |
| Compatibility | Compatible with magnetic-bead purification of DNA libraries, RNA libraries and multiplex amplification products. |
| Application Notes / Precautions | Optimize the bead and buffer ratios for the desired lower fragment-size cutoff. |
For research use only, not for clinical use.
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