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| Product Name | Human OTR (Oxytocin Receptor) ELISA Kit |
| Catalog No. | HTK-YJL-0010 |
| Synonyms | Oxytocin Receptor ELISA Kit, OT-R ELISA Kit, OXTR ELISA Kit |
| Species | Human |
| UniProt ID | P30559 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antibody |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 0.156-10 ng/ml |
| Sensitivity | 0.094 ng/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with OTR, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
Oxytocin, often referred to as the "bonding hormone" or "love hormone," plays a pivotal role in a wide range of physiological and behavioral processes in humans. It is involved in social bonding, maternal-infant attachment, emotional regulation, stress response modulation, and even reproductive functions such as uterine contractions and lactation. The biological effects of oxytocin are primarily mediated through its specific binding to the Oxytocin Receptor (OTR), a G protein-coupled receptor (GPCR) expressed in various tissues and organs including the brain, uterus, mammary glands, and immune cells.
Research on OTR has gained significant traction in recent years due to its implications in multiple scientific fields. For instance:
In neuroscience, OTR expression patterns and signaling pathways are closely linked to social behavior, anxiety, depression, and cognitive functions, making it a key target for understanding neuropsychiatric disorders.
In reproductive biology, OTR-mediated oxytocin actions are critical for parturition and lactation, driving studies on maternal health and fertility-related research.
In immunology, emerging evidence suggests that OTR signaling modulates immune cell activity and inflammatory responses, opening new avenues for investigating immune-related diseases.
Target-specific design that selectively recognizes human OTR (UniProt ID: P30559), ensuring minimal cross-reactivity with other related receptors or proteins.
Wide sample compatibility, accommodating serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples to suit diverse experimental setups.
Sandwich ELISA detection format with double antibody recognition, enhancing assay specificity and signal stability for consistent results.
Broad dynamic range of 0.156-10 ng/ml, enabling the quantification of both low and high OTR concentrations in a single assay without sample dilution or concentration.
High sensitivity with a detection limit of 0.094 ng/ml, facilitating the detection of trace amounts of OTR in samples with low expression levels.
Streamlined experimental workflow with a total reaction duration of just 4 hours, saving time and improving laboratory efficiency.
Stable storage conditions at 2-8°C (sealed, no cryopreservation required), ensuring product performance and shelf life under standard laboratory storage.
Exceptional specificity eliminates interference from non-target analytes, guaranteeing accurate and trustworthy quantification of OTR.
High sensitivity allows for the detection of subtle changes in OTR levels, supporting research on dynamic biological processes and low-expression samples.
User-friendly protocol that does not require specialized equipment or advanced technical skills, making it accessible to researchers across different laboratory settings.
Reproducible results with low intra-assay and inter-assay variability, ensuring consistency across multiple experiments and reducing experimental errors.
Versatile application scope covers neuroscience, reproductive biology, immunology, and other related research fields, meeting the diverse needs of scientific investigations.
Reliable performance backed by rigorous quality control standards, ensuring each kit meets predefined specifications for sensitivity, specificity, and linearity.
For research use only, not for clinical use.
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