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| Product Name | Human MTHFR C677T Genotyping qPCR Kit for Whole Blood |
| Catalog No. | ASNPGDK-0002 |
| Description | The Alta DiagnoTech human MTHFR genotyping kit uses fluorescent-probe PCR with whole-blood samples. It evaluates the common C677T polymorphism, which is associated with altered MTHFR enzyme activity and differences in folate metabolism. |
| Intended Use | Assessment of folate-metabolism capacity to support individualized folic-acid supplementation before and during pregnancy, and to provide reference information for cardiovascular and cerebrovascular risk evaluation. |
| Principle / Technology | Fluorescent-probe PCR genotyping of the MTHFR C677T polymorphism. |
| Detection Method | PCR with fluorescent probe detection |
| Sample Type | Whole blood |
| Performance Range / Specifications | MTHFR enzyme activity in CT and TT genotypes is approximately 65% and 30%, respectively, of the activity associated with the CC genotype. |
| Key Features | Whole-blood testing Fluorescent-probe PCR C677T polymorphism analysis Supports individualized folate assessment |
| Product Type | Human gene genotyping kit |
| Analytes / Targets | Human MTHFR gene |
| Genotypes / Variants Detected | MTHFR C677T; CC, CT and TT genotypes |
| Applicable Population | Couples preparing for pregnancy; women in early or mid-pregnancy; women with a history of adverse pregnancy outcomes; and people with hyperhomocysteinemia or cardiovascular disease. |
For research use only, not for clinical use.
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