Human MTHFR C677T Genotyping qPCR Kit for Whole Blood
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Human MTHFR C677T Genotyping qPCR Kit for Whole Blood

Cat.No: ASNPGDK-0002 Datasheet

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Product Name Human MTHFR C677T Genotyping qPCR Kit for Whole Blood
Catalog No. ASNPGDK-0002
Description The Alta DiagnoTech human MTHFR genotyping kit uses fluorescent-probe PCR with whole-blood samples. It evaluates the common C677T polymorphism, which is associated with altered MTHFR enzyme activity and differences in folate metabolism.
Intended Use Assessment of folate-metabolism capacity to support individualized folic-acid supplementation before and during pregnancy, and to provide reference information for cardiovascular and cerebrovascular risk evaluation.
Principle / Technology Fluorescent-probe PCR genotyping of the MTHFR C677T polymorphism.
Detection Method PCR with fluorescent probe detection
Sample Type Whole blood
Performance Range / Specifications MTHFR enzyme activity in CT and TT genotypes is approximately 65% and 30%, respectively, of the activity associated with the CC genotype.
Key Features Whole-blood testing
Fluorescent-probe PCR
C677T polymorphism analysis
Supports individualized folate assessment
Product Type Human gene genotyping kit
Analytes / Targets Human MTHFR gene
Genotypes / Variants Detected MTHFR C677T; CC, CT and TT genotypes
Applicable Population Couples preparing for pregnancy; women in early or mid-pregnancy; women with a history of adverse pregnancy outcomes; and people with hyperhomocysteinemia or cardiovascular disease.

For research use only, not for clinical use.

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