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| Product Name | Human CYP2D6*10 Genotyping ARMS-qPCR Kit for 1-100 ng/µL Genomic DNA Input |
| Catalog No. | ASNPGDK-0004 |
| Description | The Alta DiagnoTech human CYP2D6 genotyping kit uses ARMS-PCR to assess CYP2D6*10. This polymorphism can influence the metabolism of metoprolol and other drugs, including antipyrine, codeine, tramadol and tamoxifen, and may support individualized treatment decisions. |
| Intended Use | CYP2D6*10 genotyping to inform selection and dosing of metoprolol and other drugs whose metabolism is affected by CYP2D6 activity. |
| Principle / Technology | ARMS-PCR genotyping with fluorescent detection and contamination-control chemistry. |
| Detection Method | ARMS-PCR with fluorescent detection |
| Performance Range / Specifications | Minimum detectable genomic DNA concentration: 1 ng/µL; maximum tolerated genomic DNA concentration: 100 ng/µL; within-run and between-run Ct CV below 5%. |
| Sensitivity / LOD | 1 ng/µL human genomic DNA |
| Specificity | ARMS-PCR is used for high-specificity and high-accuracy genotyping of unknown samples. |
| Components / Formulation | Anti-contamination component. |
| Quality Control | Within-run and between-run Ct coefficient of variation below 5%. |
| Key Features | CYP2D6*10 pharmacogenomic assessment ARMS-PCR genotyping 1-100 ng/µL genomic DNA input range Ct precision below 5% CV |
| Product Type | Human gene genotyping kit |
| Analytes / Targets | Human CYP2D6 gene |
| Genotypes / Variants Detected | CYP2D6*10; the page discusses comparison with CYP2D6*1 wild type. |
For research use only, not for clinical use.
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