EPI (Epinephrine/Adrenaline) ELISA Kit

Epinephrine, also known as adrenaline, is a critical catecholamine hormone and neurotransmitter that plays pivotal roles in regulating numerous physiological processes across the human body and other organisms. It is primarily synthesized and secreted by the adrenal medulla, with additional production in certain neurons of the central and peripheral nervous systems.

Physiologically, epinephrine acts as a key mediator of the body’s "fight-or-flight" response, triggered by stress, danger, or physical exertion. Upon release, it binds to adrenergic receptors (α and β subtypes) distributed in various tissues, initiating rapid physiological changes. These include increasing heart rate, enhancing cardiac contractility, dilating bronchial airways, constricting peripheral blood vessels to redirect blood flow to vital organs (such as the heart, brain, and muscles), and elevating blood glucose levels by promoting glycogenolysis in the liver and muscles.
Beyond its role in acute stress responses, epinephrine is involved in maintaining baseline physiological homeostasis, including regulating blood pressure, metabolism, and immune function. Abnormal levels of epinephrine are closely associated with a range of pathological conditions. For example, excessive secretion may contribute to hypertension, arrhythmias, anxiety disorders, and pheochromocytomas (tumor-induced catecholamine excess). Conversely, insufficient epinephrine production can be linked to certain endocrine disorders or neurological conditions affecting catecholamine synthesis or release.
In research settings, accurate quantification of epinephrine in biological samples is essential for advancing understanding in multiple fields. This includes studies on stress physiology, neuropharmacology, cardiovascular research, endocrinology, and psychiatric research. Reliable measurement of epinephrine levels enables researchers to investigate disease mechanisms, evaluate the efficacy of therapeutic interventions, and explore the role of this hormone in various physiological and pathological processes. The EPI (Epinephrine/Adrenaline) ELISA Kit is specifically designed to meet this critical research need, providing a sensitive and specific tool for quantitative analysis of epinephrine in diverse biological samples.