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| Product Name | Human NLRP3 (Nod Like Receptor Pyrins-3) ELISA Kit |
| Catalog No. | HTK-YJL-0375 |
| Synonyms | NACHT, LRR And PYD Domains-containing Protein 3 ELISA Kit, Angiotensin/vasopressin Receptor AII/AVP-like ELISA Kit, Caterpiller Protein 1.1 ELISA Kit, CLR1.1 ELISA Kit, Cold-induced Autoinflammatory Syndrome 1 Protein ELISA Kit, Cryopyrin ELISA Kit, PYRIN-containing APAF1-like Protein 1 ELISA Kit, NLRP3 ELISA Kit, C1orf7 ELISA Kit, CIAS1 ELISA Kit, NALP3 ELISA Kit, PYPAF1 ELISA Kit |
| Species | Human |
| UniProt ID | Q96P20 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antibody |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 0.781-50 ng/ml |
| Sensitivity | 0.469 ng/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with NLRP3, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
| Product Introduction | The NOD-like receptor pyrin 3 (NLRP3) is a key component of the inflammasome complex, playing a central role in the innate immune response. It recognizes various danger signals and triggers caspase-1 activation, leading to the maturation of pro-inflammatory cytokines IL-1β and IL-18. Research on NLRP3 is crucial for understanding inflammatory diseases, autoimmune disorders, and infection responses. The Alta DiagnoTech human NLRP3 ELISA kit provides a reliable tool for quantifying NLRP3 protein levels in human cell lysates and tissue homogenates. |
| Product Application | • Inflammasome and innate immunity research • Autoimmune and inflammatory disease studies • Infection and host response mechanisms • Drug discovery and therapeutic development |
| Product Advantages | • High Sensitivity: Capable of detecting endogenous NLRP3 levels in various sample types • Excellent Specificity: Minimal cross-reactivity with other NLRP family members • Consistent Performance: Low intra- and inter-assay variation for reliable results • User-Friendly Protocol: Straightforward procedure requiring minimal hands-on time |
For research use only, not for clinical use.
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