CAPSO biological buffer, CAS 73463-39-5, pKa 9.8
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CAPSO biological buffer, CAS 73463-39-5, pKa 9.8

Cat.No: ATR-B-YJL-0212 Datasheet

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Product Name CAPSO biological buffer, CAS 73463-39-5, pKa 9.8
Catalog No. ATR-B-YJL-0212
Description 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, also known as CAPSO, is a zwitterionic buffer belonging to the sulfonic acid class of chemical compounds. It is highly useful in a variety of scientific applications, including biochemistry, molecular biology, and pharmacology. CAPSO is a buffer with a pKa of 9.8 and dissolves readily in water. It is widely used in biological applications because it is chemically stable and does not interfere with biological processes. The compound possesses both amine and sulfonic acid groups, allowing it to act as either a weak acid or a weak base within a buffering system. Its pKa of 9.8 makes it an effective buffer in the near-neutral to alkaline range. CAPSO is highly water-soluble, which simplifies the preparation of solutions at various concentrations, and it remains stable across a wide range of pH, temperature, and ionic strength conditions.
Intended Use Owing to its stability and distinctive properties, CAPSO is widely used as a buffer in biological and biochemical applications. It is commonly used in cell culture media, protein purification, and chromatography. CAPSO also serves as a buffer for electrophoresis, a technique used to separate and analyze DNA, RNA, and proteins, where it offers several advantages including a narrow buffering range, strong buffering capacity, and low ultraviolet absorbance. In addition, CAPSO is used in the production of vaccines, cosmetics, and pharmaceuticals, where its stability and safety make it an ideal ingredient.
Package Specifications 25 kg/drum
Product Form White crystalline powder
Key Features pKa of 9.8, effective in the near-neutral to alkaline range
Unique amine and sulfonic acid groups allow it to act as both a weak acid and a weak base
Highly water-soluble for easy preparation of solutions at various concentrations
Stable across a wide range of pH, temperature, and ionic strength conditions
Narrow buffering range, strong buffering capacity, and low UV absorbance for electrophoresis
Purity >99%
Molecular Weight 255.36
pH Range / Optimal pH pKa 9.8 (near-neutral to alkaline buffering range)
Molecular Formula C9H19NO4S
Appearance White crystalline powder
Alias CAPSO; 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid
Solubility Readily soluble in water
CAS Number 73463-39-5
pKa 9.8

For research use only, not for clinical use.

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