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| Product Name | Bis-tris hydrochloride buffer for patch clamp electrophysiology, CAS 124763-51-5, pH 5.8-7.2 |
| Catalog No. | ATR-B-YJL-0211 |
| Description | BIS-TRIS hydrochloride is a white crystalline powder that dissolves readily in water and is used as a versatile buffer in biochemical assays, electrophysiology, and biophysical research. It maintains pH stability between 5.8 and 7.2 and is used in protein and enzyme assays, DNA and RNA sequencing, and biomolecule purification. It also supports the preparation of media for cell culture, bacterial growth, and virus propagation. Because of its low toxicity and minimal effect on investigated ion channels, BIS-TRIS hydrochloride is used as an intracellular buffer in patch clamp experiments. It remains relatively stable at elevated temperatures and does not require special storage conditions. |
| Intended Use | For use as a biological buffer in biochemical assays, protein and enzyme analysis, nucleic acid sequencing, biomolecule purification, culture media preparation, biophysical research, and patch clamp electrophysiology. |
| Principle / Technology | BIS-TRIS hydrochloride maintains stable pH conditions from 5.8 to 7.2. Its low toxicity and limited interaction with ion channels make it suitable for intracellular buffering during patch clamp measurements. |
| Storage Conditions | No special storage conditions are required. The product is relatively stable at elevated temperatures. |
| Package Specifications | 25 kg per drum |
| Product Form | Crystalline powder |
| Key Features | Readily soluble in water Maintains pH stability between 5.8 and 7.2 Suitable for biochemical, biophysical, and electrophysiological assays Low toxicity with minimal effect on investigated ion channels Compatible with reducing and non-reducing conditions Does not interfere with biological samples or target biomolecules |
| Purity | >99% |
| Molecular Weight | 245.7 g/mol |
| pH Range / Optimal pH | 5.8-7.2 |
| Compatibility | Compatible with both reducing and non-reducing conditions. |
| Molecular Formula | C8H20ClNO5 |
| Appearance | White crystalline powder |
| Alias | BIS-TRIS-HCl; BIS-TRIS hydrochloride; 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol hydrochloride |
| Solubility | Readily soluble in water |
| CAS Number | 124763-51-5 |
For research use only, not for clinical use.
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