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| Product Name | Rat CT (Calcitonin) ELISA Kit |
| Catalog No. | HTK-YJL-0001 |
| Synonyms | CT ELISA Kit, Calcitonin ELISA Kit, Thyrocalcitonin ELISA Kit |
| Species | Rat |
| UniProt ID | P01257 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antibody |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 15.625-1000 pg/ml |
| Sensitivity | 9.375 pg/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with CT, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
Calcitonin (CT) is a peptide hormone primarily secreted by the parafollicular cells (C cells) of the thyroid gland in rats. It plays a critical role in regulating calcium and phosphorus metabolism, acting as a counterbalance to parathyroid hormone (PTH) to maintain mineral homeostasis. By inhibiting osteoclast activity, CT reduces bone resorption and decreases the release of calcium into the bloodstream, while also promoting calcium excretion through the kidneys.
In research settings, the accurate detection of rat CT levels is essential for studying various physiological and pathological processes. It is widely used in investigations related to osteoporosis, thyroid function disorders, bone metabolism diseases, and the development of therapeutic agents targeting calcium regulation. Additionally, rat CT serves as a key biomarker in preclinical studies evaluating the efficacy of drugs affecting bone health or endocrine function.
ELISA (Enzyme-Linked Immunosorbent Assay) has become the gold standard for CT detection due to its high specificity, sensitivity, and reproducibility. The Rat CT (Calcitonin) ELISA Kit is designed to meet the growing demand for reliable quantitative analysis of CT in rat samples, enabling researchers to obtain precise data for their experiments.
Target-specific design that selectively recognizes rat Calcitonin (CT) without cross-reacting with other related peptides or hormones.
Broad sample compatibility, supporting the analysis of serum, plasma, cell culture supernatant, cell lysate, tissue lysate, and other liquid samples commonly used in research.
Sandwich ELISA detection format with double antibody specificity, ensuring high binding affinity and accurate quantification of CT levels.
Clear detection wavelength at OD450 nm, compatible with standard microplate readers for convenient result measurement.
Moderate reaction duration of 4 hours, balancing efficiency and assay performance for laboratory workflow optimization.
Defined detection range of 15.625-1000 pg/ml, covering the physiological concentration range of CT in rat samples.
High sensitivity of 9.375 pg/ml, enabling the detection of low-abundance CT levels for sensitive research applications.
Stable storage conditions at 2-8°C (sealed, no cryopreservation required), ensuring long-term product integrity and usability.
Reliable specificity minimizes false-positive results, providing researchers with trustworthy data for their experimental conclusions.
Versatile sample compatibility eliminates the need for specialized sample preparation, saving time and reducing experimental complexity.
High sensitivity allows for the detection of subtle changes in CT levels, making it suitable for studies requiring precise concentration measurements.
Reproducible assay performance ensures consistent results across multiple experiments and between different laboratories.
User-friendly protocol with clear instructions, suitable for both experienced researchers and laboratory personnel new to ELISA techniques.
Cost-effective quantitative solution compared to alternative detection methods, supporting large-scale research projects and routine sample analysis.
Strict quality control during production guarantees batch-to-batch consistency, maintaining the reliability of experimental outcomes.
For research use only, not for clinical use.
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