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| Product Name | Mouse AT1R (Angiotensin Ⅱ Receptor Type 1) ELISA Kit |
| Catalog No. | HTK-YJL-0012 |
| Synonyms | Type-1 Angiotensin II Receptor ELISA Kit, AT1AR ELISA Kit, AT1BR ELISA Kit, Angiotensin II Type-1 Receptor ELISA Kit, AGTR1 ELISA Kit, AGTR1A ELISA Kit, AGTR1B ELISA Kit, AT2R1 ELISA Kit, AT2R1B ELISA Kit |
| Species | Mouse |
| UniProt ID | Q9WVK0 |
| Sample Type | Serum, plasma, cell culture supernatant, cell or tissue lysate, other liquid samples |
| Detection Method | Sandwich ELISA, Double Antibody |
| Detection Wavelength | OD450 |
| Reaction Duration | 4 hours |
| Range | 78.125-5000 pg/ml |
| Sensitivity | 46.875 pg/ml |
| Storage | 2-8°C (Sealed). Don't cryopreserve. |
| Specificity | Specifically binds with AT1R, no obvious cross reaction with other analogues. |
| Intended Use | For research use only. |
Angiotensin Ⅱ Receptor Type 1 (AT1R), encoded by the AGTR1 gene (UniProt ID: Q9WVK0), is a key G protein-coupled receptor involved in the renin-angiotensin-aldosterone system (RAAS). It plays a critical role in regulating vascular tone, fluid balance, and blood pressure, making it a core target for cardiovascular research.
AT1R is widely expressed in tissues such as the heart, kidneys, blood vessels, and brain. Its activation by angiotensin Ⅱ triggers downstream signaling pathways related to cell proliferation, fibrosis, and inflammation, which are closely linked to the pathogenesis of hypertension, heart failure, and renal diseases.
Research on AT1R expression levels and functional activity is essential for understanding disease mechanisms, developing targeted therapies, and evaluating drug efficacy. ELISA kits dedicated to AT1R detection have become indispensable tools for researchers in pharmacology, physiology, and molecular biology.
The Mouse AT1R ELISA Kit is designed to specifically quantify AT1R in various mouse-derived samples, enabling accurate and reliable analysis to support preclinical research and basic science investigations.
Species-specific design tailored for mouse samples, ensuring high compatibility with serum, plasma, cell culture supernatant, cell lysate, and tissue lysate.
Sandwich ELISA technology with double antibody recognition, minimizing non-specific binding and enhancing detection specificity.
Broad dynamic range of 78.125-5000 pg/ml, covering the typical concentration range of AT1R in biological samples for versatile research applications.
High sensitivity with a lower limit of detection at 46.875 pg/ml, enabling the quantification of low-abundance AT1R in dilute or limited samples.
Short reaction duration of 4 hours, streamlining experimental workflows and reducing research turnaround time.
Stable storage conditions at 2-8°C (no cryopreservation required), ensuring long-term product integrity and convenience for laboratory use.
Rigorous specificity validation, with no obvious cross-reactivity with AT1R analogues or other related proteins.
Accurate and reproducible results, supported by standardized manufacturing processes and quality control procedures to ensure batch-to-batch consistency.
User-friendly operation protocol, suitable for both experienced researchers and laboratory technicians with basic ELISA skills.
Versatile sample compatibility, eliminating the need for specialized sample preprocessing and accommodating multiple sample types in a single assay.
Cost-effective solution for high-throughput research, with 48T and 96T format options to meet different experimental scales and budget requirements.
Reliable specificity ensures that only AT1R is detected, avoiding false-positive results that could compromise research data.
Validated for research use, aligning with the needs of preclinical studies and basic science research to drive impactful discoveries.
For research use only, not for clinical use.
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